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Effect of recombinant human granulocyte colony-stimulating factor on human neutrophil adherence in vitro.

作者信息

Okada Y, Kawagishi M, Kusaka M

机构信息

Pharmaceutical Laboratory, Kirin Brewery Co. Ltd, Gunma Prefecture, Japan.

出版信息

Experientia. 1990 Oct 15;46(10):1050-3. doi: 10.1007/BF01940670.

DOI:10.1007/BF01940670
PMID:1699783
Abstract

We measured the effects of recombinant human granulocyte-colony stimulating factor (rhG-CSF) on the adherence of human neutrophils by using a dacron fiber system to assay the adhesive ability of neutrophils. rhG-CSF enhanced neutrophil adherence to dacron fibers. N-formyl-methionyl-leucyl-phenylalanine (fMLP) induced neutrophil-neutrophil interaction (neutrophil aggregation) in addition to neutrophil-dacron interaction, whereas rhG-CSF did not cause neutrophil aggregation. These results indicated that rhG-CSF increases the adhesive ability of neutrophils without neutrophil-neutrophil interaction, and the action of rhG-CSF in neutrophil activation is different from the neutrophil activation caused by fMLP.

摘要

相似文献

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引用本文的文献

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本文引用的文献

1
Proliferative effects of purified granulocyte colony-stimulating factor (G-CSF) on normal mouse hemopoietic cells.纯化的粒细胞集落刺激因子（G-CSF）对正常小鼠造血细胞的增殖作用。
J Cell Physiol. 1983 Aug;116(2):198-206. doi: 10.1002/jcp.1041160211.
2
Effects of adrenergic alpha- and beta-receptor stimulation on the release of lymphocytes and granulocytes from the spleen.肾上腺素能α和β受体刺激对脾脏淋巴细胞和粒细胞释放的影响。
Scand J Haematol. 1973;11(4):275-86. doi: 10.1111/j.1600-0609.1973.tb00130.x.
3
A monoclonal antibody-defined membrane antigen complex is required for neutrophil-neutrophil aggregation.
中性粒细胞-中性粒细胞聚集需要一种单克隆抗体定义的膜抗原复合物。
Blood. 1985 Jun;65(6):1553-6.
4
Purification and biochemical characterization of human pluripotent hematopoietic colony-stimulating factor.人多能造血集落刺激因子的纯化及生化特性分析
Proc Natl Acad Sci U S A. 1985 Mar;82(5):1526-30. doi: 10.1073/pnas.82.5.1526.
5
Purified colony-stimulating factors enhance the survival of human neutrophils and eosinophils in vitro: a rapid and sensitive microassay for colony-stimulating factors.纯化的集落刺激因子可增强人中性粒细胞和嗜酸性粒细胞在体外的存活：一种快速灵敏的集落刺激因子微量测定法。
Blood. 1986 Jul;68(1):162-6.
6
Increased surface expression of CD11b/CD18 (Mac-1) is not required for stimulated neutrophil adherence to cultured endothelium.中性粒细胞受刺激后黏附于培养的内皮细胞并不需要增加CD11b/CD18（巨噬细胞-1抗原）的表面表达。
J Clin Invest. 1988 Mar;81(3):676-82. doi: 10.1172/JCI113372.
7
Effects of recombinant human granulocyte and macrophage colony-stimulating factors on signal transduction pathways in human granulocytes.重组人粒细胞和巨噬细胞集落刺激因子对人粒细胞信号转导途径的影响。
J Immunol. 1987 Nov 15;139(10):3422-30.
8
Recombinant human granulocyte colony-stimulating factor enhances superoxide release in human granulocytes stimulated by the chemotactic peptide.重组人粒细胞集落刺激因子增强趋化肽刺激的人粒细胞中超氧化物的释放。
Biochem Biophys Res Commun. 1987 May 14;144(3):1143-6. doi: 10.1016/0006-291x(87)91430-6.
9
Down-modulation of receptors for granulocyte colony-stimulating factor on human neutrophils by granulocyte-activating agents.
J Cell Physiol. 1986 Sep;128(3):501-9. doi: 10.1002/jcp.1041280320.
10
The effect of intravascular neutrophil chemotactic factors on blood neutrophil and platelet kinetics.血管内中性粒细胞趋化因子对血液中性粒细胞及血小板动力学的影响。
Am J Hematol. 1986 Feb;21(2):157-71. doi: 10.1002/ajh.2830210205.