Chen P L, Wang P Y, Sheu W H, Chen Y T, Ho Y P, Hu H H, Hsu H Y
Section of Neurology, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung-Kang Rd., Taichung 407, Taiwan, ROC.
Neurology. 2006 Sep 26;67(6):1056-8. doi: 10.1212/01.wnl.0000237526.32692.67.
The relationship between endothelial dysfunction and stroke subtypes is unclear. We prospectively measured brachial flow-mediated vasodilation (FMD) in 143 patients with acute ischemic stroke and 40 controls. The overall stroke patients had impaired FMD, but only lacunar infarction had significantly impaired FMD vs the controls. Impaired FMD was an independent predictor for lacunar infarction. Ischemic stroke is associated with endothelial dysfunction, which is more conspicuous in lacunar infarction.
内皮功能障碍与卒中亚型之间的关系尚不清楚。我们前瞻性地测量了143例急性缺血性卒中患者和40例对照者的肱动脉血流介导的血管舒张功能(FMD)。总体卒中患者的FMD受损,但只有腔隙性脑梗死患者的FMD与对照组相比有显著受损。FMD受损是腔隙性脑梗死的独立预测因素。缺血性卒中与内皮功能障碍有关,这在腔隙性脑梗死中更为明显。