de Graaff M J, Buijs R M, Hoekstra J B L, Fliers E, Holleman F
Academisch Medisch Centrum/Universiteit van Amsterdam, Meiberg-dreef 9, 11005 AZ Amsterdam.
Ned Tijdschr Geneeskd. 2006 Sep 9;150(36):1971-5.
The number of indications for the medical use of melatonin is slowly increasing. Melatonin is produced by the pineal gland and is a key signal in the circadian rhythm of the body. Melatonin plays an obvious role in the pathophysiology and treatment of sleep disorders and jetlag. Recent research has also demonstrated its favourable effect on blood-pressure regulation. By analogy, melatonin may play a role in a variety of other circadian processes. However, research into the precise effects is still insufficient.
褪黑素在医学上的应用指征数量正在缓慢增加。褪黑素由松果体分泌，是人体昼夜节律中的关键信号。褪黑素在睡眠障碍和时差反应的病理生理学及治疗中发挥着明显作用。最近的研究还表明其对血压调节有积极作用。同理，褪黑素可能在多种其他昼夜节律过程中发挥作用。然而，对其确切作用的研究仍不充分。
