Takata Yutaka, Ansai Toshihiro, Akifusa Sumio, Soh Inho, Sonoki Kazuo, Takehara Tadamichi
Division of General Internal Medicine, Department of Health Promotion, Kyushu Dental College, Kitakyushu, Japan.
Gerontology. 2007;53(1):46-51. doi: 10.1159/000095934. Epub 2006 Sep 25.
Little is known about the relationship between high-level functional capacity and mortality in elderly people.
To evaluate the relationship between high-level functional capacity, such as intellectual activity and social role, and 4-year mortality in a population of 80-year-old community residents.
Participating in the study were 697 individuals (277 males and 420 females) out of 1,282 80-year-old individuals residing in Fukuoka Prefecture, Japan. To measure high-level functional capacity, the daily activities of 656 of the 697 participants were examined through questionnaires, accompanied by physical and laboratory blood examinations. The 697 participants were followed up for 4 years after the baseline examination. For subjects who died during that period, the date and cause of death were recorded from resident registration cards and official death certificates.
The relative risk for all-cause mortality decreased with an increase in intellectual activity or total functional capacity, whereas no association was found between total mortality and either the ability to perform instrumental self-maintenance or the ability to maintain a social role. Similarly, the relative mortality risk due to cardiovascular diseases decreased with an increase in intellectual activity or total functional capacity. Mortality due to pneumonia also decreased with an increase in intellectual activity.
In a population of 80-year-old community residents, levels of intellectual activity and total functional capacity may be associated with all-cause, cardiovascular, and pneumonia mortality, and may be strong predictors of survival.
关于老年人高水平功能能力与死亡率之间的关系，人们了解甚少。
评估诸如智力活动和社会角色等高水平功能能力与80岁社区居民人群4年死亡率之间的关系。
在日本福冈县居住的1282名80岁个体中，有697人（277名男性和420名女性）参与了该研究。为测量高水平功能能力，通过问卷调查对697名参与者中的656人的日常活动进行了检查，并进行了身体和实验室血液检查。在基线检查后对697名参与者进行了4年的随访。对于在此期间死亡的受试者，从居民登记卡和官方死亡证明中记录了死亡日期和原因。
全因死亡率的相对风险随着智力活动或总功能能力的增加而降低，而总死亡率与工具性自我维持能力或维持社会角色的能力之间均未发现关联。同样，心血管疾病导致的相对死亡风险随着智力活动或总功能能力的增加而降低。肺炎导致的死亡率也随着智力活动的增加而降低。
在80岁社区居民人群中，智力活动水平和总功能能力可能与全因、心血管和肺炎死亡率相关，并且可能是生存的有力预测指标。
