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乳糜胸

Chylothorax.

作者信息

Platis Ioannis E, Nwogu Chumy E

机构信息

General Surgery Program, State University of New York at Buffalo, 193 Summer Street, Buffalo, NY 14222, USA.

出版信息

Thorac Surg Clin. 2006 Aug;16(3):209-14. doi: 10.1016/j.thorsurg.2006.05.011.

Abstract

Chylothorax is a rare complication of pulmonary resection. It requires prompt treatment, which is initially conservative. This treatment consists of drainage, nutritional support, and measures to diminish chyle flow. Surgical intervention is indicated when conservative management is ineffective. Delay in surgical intervention leads not only to serious metabolic, nutritional, and immunologic disturbances from the loss of chyle but also increases the risk for adhesion formation, loculation, organization, and infection of the chylothorax, making subsequent surgical attempts difficult and increasing postoperative morbidity and mortality. VATS provides a minimally invasive approach for the treatment of chylothorax complicating pulmonary resection. Clipping of the thoracic duct or chemical pleurodesis may be performed with minimal morbidity and mortality. Conservative treatment is expensive and fails in most patients who have high-output chylous fistulae. On the other hand, VATS is uniformly effective, is less expensive, and has low morbidity. Indeed, VATS is rapidly becoming the preferred approach for the management of chylothorax complicating pulmonary resection. The need to prevent the occurrence of a chylothorax by careful dissection techniques and liberal clipping of lymphatic vessels particularly in areas of high anatomic risk during the initial operation cannot be overemphasized.

摘要

乳糜胸是肺切除术后一种罕见的并发症。它需要及时治疗,初始治疗为保守治疗。这种治疗包括引流、营养支持以及减少乳糜流量的措施。当保守治疗无效时,需进行手术干预。延迟手术干预不仅会因乳糜丢失导致严重的代谢、营养和免疫紊乱,还会增加乳糜胸形成粘连、分隔、机化和感染的风险,使后续手术难度增大,并增加术后发病率和死亡率。电视辅助胸腔镜手术(VATS)为治疗肺切除术后并发的乳糜胸提供了一种微创方法。胸导管结扎或化学性胸膜固定术的实施,发病率和死亡率可降至最低。保守治疗费用高昂,且对大多数存在高流量乳糜瘘的患者无效。另一方面,VATS疗效确切、费用较低且发病率低。事实上,VATS正迅速成为治疗肺切除术后并发乳糜胸的首选方法。在初次手术时,通过精细的解剖技术和对淋巴管的广泛结扎来预防乳糜胸的发生,尤其是在解剖风险较高的区域,这一点再怎么强调都不为过。

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