Ball A P, Gray J A, Murdoch J M
Drugs. 1975;10(2):81-111. doi: 10.2165/00003495-197510020-00001.
Since the development of the sulphonamides in the 1930s and the subsequent development of antibiotics from the 1940s onwards, there have now been many drugs developed which are capable of chemotherapeutic activity in a patient infected by a susceptible micro-organism. This review is concerned with precise descriptions of important groups of antimicrobial drugs, with emphasis being placed on the more recently developed drugs. With each group of drugs the pharmacology, major therapeutic indications, dosages and adverse reactions are discussed. Part II of the review discusses the cephalosporins, polymyxins and aminoglycosides. The place of each in therapy is defined.
自20世纪30年代磺胺类药物问世以及随后从40年代起抗生素得到发展以来，如今已研发出许多药物，这些药物在感染了易感微生物的患者体内具有化疗活性。本综述关注抗菌药物重要类别的确切描述，重点放在较新研发的药物上。针对每类药物，都讨论了其药理学、主要治疗适应证、剂量和不良反应。综述的第二部分讨论了头孢菌素、多粘菌素和氨基糖苷类药物。明确了每类药物在治疗中的地位。
