Bellin Marie-France
University Paris-Sud XI, Department of Radiology, University Hospital Paul-Brousse, AP-HP, 12, Avenue Paul Vaillant-Couturier, 94804 Villejuif Cedex, France.
Eur J Radiol. 2006 Dec;60(3):314-23. doi: 10.1016/j.ejrad.2006.06.021. Epub 2006 Sep 26.
Magnetic resonance (MR) contrast agents are increasingly being used to help detect and characterize various neoplastic, inflammatory and functional abnormalities. The extracellular, non-specific contrast agents gadolinium chelates are by far the most widely used. Over the past few years a number of MR organ specific contrast agents have been introduced. MRI contrast agents are generally safe and well tolerated. The present review summarizes the properties, main characteristics and imaging applications of commercially available compounds as well as safety of these agents in normal and high-risk patients.
磁共振（MR）造影剂正越来越多地用于帮助检测和鉴别各种肿瘤、炎症及功能异常。细胞外非特异性造影剂钆螯合物是目前应用最为广泛的。在过去几年中，已推出了多种MR器官特异性造影剂。MRI造影剂一般安全性良好且耐受性佳。本综述总结了市售化合物的特性、主要特点、成像应用以及这些造影剂在正常和高危患者中的安全性。
