Kotilingam Dhanasekaran, Lev Dina Chelouche, Lazar Alexander J F, Pollock Raphael E
The University of TexasMD Anderson Cancer Center, Houston, TX, USA.
CA Cancer J Clin. 2006 Sep-Oct;56(5):282-91; quiz 314-5. doi: 10.3322/canjclin.56.5.282.
Soft tissue sarcoma (STS) is an extremely heterogeneous group of rare tumors that share a putative mesenchymal cell origin. STS can occur in any soft tissue in the body, yet all share a common feature of primarily disseminating hematogenously, particularly to the lungs. Staging for STS is particularly useful in prognosis, design of effective multimodality treatment programs, and comparing treatment outcomes from different centers and different eras. The current iteration of AJCC STS staging includes Tumor, Grade, Node, and Metastasis with "a" indicating superficial and "b" indicating deep designations. Further opportunities to improve this process exist, particularly as molecular considerations become more apparent, and future evolution into an even more useful STS staging system can be anticipated.
软组织肉瘤（STS）是一组极为异质性的罕见肿瘤，它们都被认为起源于间充质细胞。STS可发生于身体的任何软组织，但都具有主要通过血行播散的共同特征，尤其是转移至肺部。STS分期对于预后评估、有效多模式治疗方案的设计以及比较不同中心和不同时期的治疗结果尤为有用。美国癌症联合委员会（AJCC）目前的STS分期版本包括肿瘤、分级、淋巴结和转移情况，其中“a”表示浅表，“b”表示深部。进一步改进这一过程仍有机会，特别是随着分子因素变得更加明显，可以预期未来会演变成一个更有用的STS分期系统。
