Chen Cheng, Wang Cheng, Li ShiJie, Zheng Xu, Yang YunFeng
Department of Orthopedics, Tongji Hospital, School of Medicine, Tongji University, Shanghai 200092, China.
Department of Orthopedics, Shanghai Sixth People's Hospital Affiliated to Shanghai JiaoTong University School of Medicine, Shanghai 200233, China.
Prev Med Rep. 2024 Oct 17;47:102903. doi: 10.1016/j.pmedr.2024.102903. eCollection 2024 Nov.
To conduct a comprehensive global epidemiological investigation of soft tissue and extraosseous sarcomas from 1990 to 2021 and uncover the demographic and geographical variations.
Incidence and death data of soft tissue and extraosseous sarcomas between 1990 and 2021 were derived from the Global Burden of Disease 2021. The estimated annual percentage change was calculated. The demographic patterns were analyzed in-depth based on age and gender.
From 1990 to 2021, there was an increase in the number and crude rate of incidence and death of soft tissue and extraosseous sarcomas, while age-standardized rate declined. Males consistently exhibited a heavier burden compared to females. The incidence and death rates of soft tissue and extraosseous sarcomas generally increased with age, with a similar pattern in both males and females. Compared to 1990, the incidence rate among the elderly increased in 2021, while the incidence rate in children under 5 decreased, and there was little change in other age groups. The death rate among children and the elderly has decreased, while little change in other age groups has been observed.
The disease burden of soft tissue and extraosseous sarcomas remains a critical challenge. Data-driven analysis is crucial for guiding clinical practice, informing public health policies, and shaping future research agendas.
对1990年至2021年期间的软组织和骨外肉瘤进行全面的全球流行病学调查，揭示人口统计学和地理差异。
1990年至2021年期间软组织和骨外肉瘤的发病率和死亡率数据来自《2021年全球疾病负担》。计算了估计的年度百分比变化。基于年龄和性别对人口统计学模式进行了深入分析。
1990年至2021年期间，软组织和骨外肉瘤的发病数、粗发病率和死亡率均有所上升，而年龄标准化率下降。男性的负担始终比女性更重。软组织和骨外肉瘤的发病率和死亡率一般随年龄增长而上升，男性和女性的模式相似。与1990年相比，2021年老年人的发病率上升，而5岁以下儿童的发病率下降，其他年龄组变化不大。儿童和老年人的死亡率有所下降，而其他年龄组变化不大。
软组织和骨外肉瘤的疾病负担仍然是一项严峻挑战。数据驱动的分析对于指导临床实践、为公共卫生政策提供信息以及制定未来研究议程至关重要。
