Jauniaux E, Gibb D, Moscoso G, Campbell S
Department of Obstetrics and Gynecology, King's College Hospital School of Medicine and Dentistry, University of London, England.
Am J Obstet Gynecol. 1990 Nov;163(5 Pt 1):1558-60. doi: 10.1016/0002-9378(90)90626-i.
A placental lesion associated with elevated maternal serum alpha-fetoprotein level and a positive Kleihauer-Betke test is reported. Serial ultrasonograms showed a progressive increase in the echogenicity of the lesion that corresponded to a large intervillous thrombosis after delivery. This case illustrates the importance of detailed ultrasonographic and pathologic placental investigations in pregnancies with unexplained elevated levels of alpha-fetoprotein.