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心包后切开术对冠状动脉血运重建术后心包积液和心房颤动发生率的影响。

Effects of posterior pericardiotomy on the incidence of pericardial effusion and atrial fibrillation after coronary revascularization.

作者信息

Ekim Hasan, Kutay Veysel, Hazar Abdüssemet, Akbayrak Hakan, Başel Halil, Tuncer Mustafa

机构信息

Department of Cardiovascular Surgery, Yüzüncü Yýl University, Van, Turkey.

出版信息

Med Sci Monit. 2006 Oct;12(10):CR431-4. Epub 2006 Sep 25.

PMID:17006403
Abstract

BACKGROUND

The aim of this prospective, randomized study was to assess the efficacy of posterior pericardiotomy in decreasing the prevalence of pericardial effusion and postoperative atrial fibrillation (AF).

MATERIAL/METHODS: The study was performed in 100 patients who underwent elective coronary artery bypass grafting surgery (CABG) between October 2003 and July 2005. They were randomized to receive posterior pericardiotomy (Group A) or no posterior pericardiotomy (Group B). A 4-cm longitudinal incision was made parallel and posterior to the left phrenic nerve, extending from the left inferior pulmonary vein to the diaphragm in group A patients. Posterior pericardiotomy was not performed in group B patients.

RESULTS

Early pericardial effusion developed in 6 patients (12%) of group A and 21 patients (42%) of group B; no late pericardial effusion developed in group A, but did in 3 patients (6%) of group B. The number of patients who developed postoperative AF was significantly lower in the fenestration group compared with the control group (10% vs. 30%, p < 0.010). The overall incidence of supraventricular tachycardia in patients with early pericardial effusion was significantly higher than in patients without early pericardial effusion (18 patients vs. 9 patients).

CONCLUSIONS

These findings suggest that posterior pericardiotomy reduces the prevalence of early pericardial effusion and related AF by improving pericardial drainage in patients undergoing coronary artery bypass surgery.

摘要

背景

这项前瞻性随机研究的目的是评估心包后切开术在降低心包积液患病率和术后房颤(AF)方面的疗效。

材料/方法:该研究对2003年10月至2005年7月期间接受择期冠状动脉旁路移植术(CABG)的100例患者进行。他们被随机分为接受心包后切开术(A组)或不接受心包后切开术(B组)。A组患者在左膈神经后方平行做一个4厘米长的纵向切口,从左下肺静脉延伸至膈肌。B组患者不进行心包后切开术。

结果

A组6例患者(12%)出现早期心包积液,B组21例患者(42%)出现早期心包积液;A组未出现晚期心包积液,B组有3例患者(6%)出现晚期心包积液。开窗组术后发生房颤的患者数量显著低于对照组(10%对30%,p<0.010)。早期心包积液患者室上性心动过速的总体发生率显著高于无早期心包积液的患者(18例对9例)。

结论

这些发现表明,心包后切开术通过改善冠状动脉旁路手术患者的心包引流,降低了早期心包积液及相关房颤的患病率。

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