Genta Robert M, Rugge Massimo
Pathology and Laboratory Service-113, VA North Texas Health Care System, 4500 S. Lancaster Road, Dallas, TX 75216, USA.
World J Gastroenterol. 2006 Sep 21;12(35):5622-7. doi: 10.3748/wjg.v12.i35.5622.
Although the Sydney Systems (original and updated) for the classification of gastritis have contributed substantially to the uniformity of the reporting of gastric conditions, they lack immediacy in conveying to the user information about gastric cancer risk. In this review, we summarize the current understanding of the gastric lesions associated with an increased risk for cancer, and present the rationale for a proposal for new ways of reporting gastritis. In addition to the traditional histopathological data gathered and evaluated according to the Sydney System rules, pathologists could add an assessment expressed as grading and staging of the gastric inflammatory and atrophic lesions and integrate these findings with pertinent laboratory information on pepsinogens and gastrin levels. Such an integrated report could facilitate clinicians' approach to the management of patients with gastric conditions.
尽管悉尼胃炎分类系统（原始版和更新版）对胃部疾病报告的一致性做出了重大贡献，但它们在向使用者传达胃癌风险信息方面缺乏即时性。在本综述中，我们总结了目前对与癌症风险增加相关的胃部病变的认识，并提出了关于胃炎新报告方式的建议依据。除了按照悉尼系统规则收集和评估的传统组织病理学数据外，病理学家还可以增加一项以胃炎性和萎缩性病变的分级和分期表示的评估，并将这些结果与有关胃蛋白酶原和胃泌素水平的相关实验室信息相结合。这样一份综合报告可以促进临床医生对胃部疾病患者的管理。
