厄他培南对西班牙分离出的产超广谱β-内酰胺酶大肠埃希菌和肺炎克雷伯菌的体外活性比较
Comparative in vitro activity of ertapenem against extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae isolated in Spain.
作者信息
Hernández José R, Velasco Carmen, Romero Luisa, Martínez-Martínez Luís, Pascual Alvaro
机构信息
Department of Microbiology, Faculty of Medicine, University of Seville, Av. Sánchez Pizjuán s/n, 41009 Seville, Spain.
出版信息
Int J Antimicrob Agents. 2006 Nov;28(5):457-9. doi: 10.1016/j.ijantimicag.2006.08.014. Epub 2006 Sep 27.
The in vitro activity of ertapenem was tested against extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli and Klebsiella pneumoniae isolated in Spain. Ertapenem activity was similar to that of imipenem and meropenem and better than that of the other antimicrobials tested. No differences in activity were observed regarding the origin of the isolates or type of ESBL produced.
对厄他培南的体外活性进行了测试，受试对象为在西班牙分离出的产超广谱β-内酰胺酶（ESBL）的大肠杆菌和肺炎克雷伯菌。厄他培南的活性与亚胺培南和美罗培南相似，且优于所测试的其他抗菌药物。在分离菌株的来源或所产ESBL的类型方面，未观察到活性存在差异。
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