Ringberg Håkan, Cathrine Petersson Ann, Walder Mats, Hugo Johansson P J
Regional Centre for Communicable Disease Control, Skåne County, Lund University Hospital, Lund, Sweden.
Scand J Infect Dis. 2006;38(10):888-93. doi: 10.1080/00365540600740546.
In order to evaluate the value of bacterial cultures taken from the throat, 266 patients with MRSA were retrospectively assessed. At the time when MRSA was first detected in the patient, the most frequent sites positive for MRSA were a skin lesion (110 patients, 41%), the anterior nares (109 patients, 41%), and the throat (102 patients, 38%). In 26%, 17%, and 17% of the patients, a skin lesion, the anterior nares, and the throat, respectively, were the only site where MRSA was seen. In 123 patients cultured for MRSA because of a close contact with an already known MRSA patient, 65 patients (53%) were positive for MRSA in their throat and in 40 patients (33%), throat was the only sample site with MRSA at the time when the patient was found to be MRSA positive. 146 of the 266 patients (55%) were colonized with MRSA in the throat any time throughout the period they were MRSA positive. We conclude that throat is an important reservoir for MRSA and that samples taken from the throat should be included in screening patients for MRSA.
为了评估从咽喉采集的细菌培养物的价值,我们对266例耐甲氧西林金黄色葡萄球菌(MRSA)患者进行了回顾性评估。在患者首次检测出MRSA时,MRSA检测呈阳性的最常见部位是皮肤病变处(110例患者,41%)、前鼻孔(109例患者,41%)和咽喉(102例患者,38%)。分别有26%、17%和17%的患者,皮肤病变处、前鼻孔和咽喉是唯一检测到MRSA的部位。在因与已知MRSA患者密切接触而进行MRSA培养的123例患者中,65例患者(53%)咽喉部MRSA检测呈阳性,40例患者(33%)在被检测出MRSA阳性时,咽喉是唯一检测到MRSA的样本部位。266例患者中有146例(55%)在整个MRSA阳性期间的任何时候咽喉部都被MRSA定植。我们得出结论,咽喉是MRSA的一个重要储存部位,对患者进行MRSA筛查时应采集咽喉样本。