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Plasminogen activator inhibitor-1 gene 4G/5G polymorphism in cancer patients with and without thrombosis.

作者信息

Eroglu Aydan, Ulu Arzu, Akar Nejat

机构信息

Department of Surgery and Surgical Oncology, Numune State Hospital, Konya, Turkey.

出版信息

J Thromb Thrombolysis. 2006 Oct;22(2):111-2. doi: 10.1007/s11239-006-9054-z.

DOI:10.1007/s11239-006-9054-z
PMID:17008976
Abstract
摘要

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Plasminogen activator inhibitor-1 gene 4G/5G polymorphism in cancer patients with and without thrombosis.伴有和不伴有血栓形成的癌症患者中纤溶酶原激活物抑制剂-1基因4G/5G多态性
J Thromb Thrombolysis. 2006 Oct;22(2):111-2. doi: 10.1007/s11239-006-9054-z.
2
Effect of plasminogen activator inhibitor-1 4G/5G polymorphism in Turkish deep vein thrombotic patients with and without FV1691 G-A.纤溶酶原激活物抑制剂-1 4G/5G多态性在伴有或不伴有FV1691 G-A的土耳其深静脉血栓形成患者中的作用
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3
Plasminogen activator inhibitor-1 4G/5G polymorphism in Turkish children with cerebral infarct and effect on factor V 1691 A mutation.
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Plasminogen activator inhibitor-1 (PAI-1) gene 4G/5G promoter polymorphism is seen in higher frequency in the Indian patients with deep vein thrombosis.纤溶酶原激活物抑制剂-1（PAI-1）基因 4G/5G 启动子多态性在印度深静脉血栓形成患者中更为常见。
Clin Appl Thromb Hemost. 2010 Apr;16(2):184-8. doi: 10.1177/1076029609333673. Epub 2009 May 5.
5
[Plasminogen activator inhibitor type 1 gene polymorphism and thromboses in patients with antiphospholipid syndrome].[抗磷脂综合征患者纤溶酶原激活物抑制剂1基因多态性与血栓形成]
Ter Arkh. 2013;85(1):76-84.
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The effect of the plasminogen activator inhibitor-1 4G/5G polymorphism on the thrombotic risk.纤溶酶原激活物抑制剂-1 4G/5G多态性对血栓形成风险的影响。
Thromb Res. 2008;122(6):736-42. doi: 10.1016/j.thromres.2007.09.005. Epub 2007 Oct 22.
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The association between the 4G/5G polymorphism in the promoter of the plasminogen activator inhibitor-1 gene and extension of postsurgical calf vein thrombosis.纤溶酶原激活物抑制剂-1基因启动子区4G/5G多态性与术后小腿静脉血栓形成延长之间的关联。
Blood Coagul Fibrinolysis. 2013 Apr;24(3):237-42. doi: 10.1097/MBC.0b013e328359f618.
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PAI-1 gene 4G/5G genotype: A risk factor for thrombosis in vessels of internal organs.纤溶酶原激活物抑制剂-1基因4G/5G基因型：内脏血管血栓形成的一个危险因素。
Am J Hematol. 2002 Oct;71(2):89-93. doi: 10.1002/ajh.10192.
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Plasminogen activator inhibitor-1 4G/4G-genotype is associated with cerebral sinus thrombosis in factor V Leiden carriers.纤溶酶原激活物抑制剂-1 4G/4G基因型与凝血因子V Leiden突变携带者的脑静脉窦血栓形成有关。
Thromb Haemost. 1998 Oct;80(4):706-7.
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Plasminogen activator inhibitor-1 4G/5G polymorphism, factor V Leiden, prothrombin mutations and the risk of VTE recurrence.纤溶酶原激活物抑制剂-1 4G/5G 多态性、因子 V 莱顿突变、凝血酶原突变与 VTE 复发风险。
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本文引用的文献

1
Factor V Leiden and PT G20210A mutations in cancer patients with and without venous thrombosis.伴有和不伴有静脉血栓形成的癌症患者中的凝血因子V莱顿突变和凝血酶原G20210A突变
J Thromb Haemost. 2005 Jun;3(6):1323-4. doi: 10.1111/j.1538-7836.2005.01346.x.
2
The PAI-1 gene 4G/5G polymorphism and deep vein thrombosis in patients with inherited thrombophilia.遗传性易栓症患者中PAI - 1基因4G/5G多态性与深静脉血栓形成
Clin Appl Thromb Hemost. 2003 Oct;9(4):299-307. doi: 10.1177/107602960300900405.
3
Allele 4G of gene PAI-1 associated with prothrombin mutation G20210A increases the risk for venous thrombosis.
Variant alleles in factor V, prothrombin, plasminogen activator inhibitor-1, methylenetetrahydrofolate reductase and risk of thromboembolism in metastatic colorectal cancer patients treated with first-line chemotherapy plus bevacizumab.
接受一线化疗加贝伐单抗治疗的转移性结直肠癌患者中，因子V、凝血酶原、纤溶酶原激活物抑制剂-1、亚甲基四氢叶酸还原酶的变异等位基因与血栓栓塞风险
Pharmacogenomics J. 2017 Jul;17(4):331-336. doi: 10.1038/tpj.2016.22. Epub 2016 Mar 22.
与凝血酶原突变G20210A相关的PAI-1基因4G等位基因会增加静脉血栓形成的风险。
Thromb Haemost. 2003 Dec;90(6):1061-4. doi: 10.1160/TH02-12-0305.
4
Major and potential prothrombotic genotypes in a cohort of patients with venous thromboembolism.一组静脉血栓栓塞症患者中的主要和潜在促血栓形成基因型。
Thromb Res. 2001 Dec 1;104(5):317-24. doi: 10.1016/s0049-3848(01)00384-x.
5
Effect of plasminogen activator inhibitor-1 4G/5G polymorphism in Turkish deep vein thrombotic patients with and without FV1691 G-A.纤溶酶原激活物抑制剂-1 4G/5G多态性在伴有或不伴有FV1691 G-A的土耳其深静脉血栓形成患者中的作用
Thromb Res. 2000 Feb 15;97(4):227-30. doi: 10.1016/s0049-3848(99)00164-4.
6
Arterial and venous thrombosis is not associated with the 4G/5G polymorphism in the promoter of the plasminogen activator inhibitor gene in a large cohort of US men.在美国一大群男性中，动脉和静脉血栓形成与纤溶酶原激活物抑制剂基因启动子中的4G/5G多态性无关。
Circulation. 1997 Jan 7;95(1):59-62. doi: 10.1161/01.cir.95.1.59.
7
The significance of hypofibrinolysis for the risk of recurrence of venous thromboembolism. Duration of Anticoagulation (DURAC) Trial Study Group.纤溶功能减退对静脉血栓栓塞复发风险的意义。抗凝持续时间（DURAC）试验研究组。
Thromb Haemost. 1996 Apr;75(4):607-11.
8
The two allele sequences of a common polymorphism in the promoter of the plasminogen activator inhibitor-1 (PAI-1) gene respond differently to interleukin-1 in HepG2 cells.纤溶酶原激活物抑制剂-1（PAI-1）基因启动子区一种常见多态性的两个等位基因序列，在HepG2细胞中对白细胞介素-1的反应不同。
J Biol Chem. 1993 May 25;268(15):10739-45.
9
Cloning and sequence of a cDNA coding for the human beta-migrating endothelial-cell-type plasminogen activator inhibitor.编码人β-迁移内皮细胞型纤溶酶原激活物抑制剂的cDNA的克隆与序列分析
Proc Natl Acad Sci U S A. 1986 Sep;83(18):6776-80. doi: 10.1073/pnas.83.18.6776.