Hsu J R, Chang S C, Perng R P
Chest Department, Veterans General Hospital-Taipei, Taiwan, Republic of China.
Chest. 1990 Dec;98(6):1512-3. doi: 10.1378/chest.98.6.1512.
Pneumothorax occurring as a complication of the antitumor effect of cytotoxic chemotherapy has been reported in occasional cases of a variety of tumors. Its occurrence in malignant lymphoma has not been reported heretofore. In this report, we describe two cases of this complication in patients with malignant lymphoma and discuss the possible pathophysiologic mechanisms involved. Because pulmonary involvement with the tumor was found in both cases, pneumothorax could be attributed to the anti-tumor effect of cytotoxic agents on underlying lung involvement in patients with malignant lymphoma.
作为细胞毒性化疗抗肿瘤作用的并发症，气胸在多种肿瘤的个别病例中已有报道。迄今为止，尚未见其在恶性淋巴瘤中发生的报道。在本报告中，我们描述了两例恶性淋巴瘤患者发生这种并发症的情况，并讨论了可能涉及的病理生理机制。由于两例均发现有肺部肿瘤累及，气胸可归因于细胞毒性药物对恶性淋巴瘤患者潜在肺部累及的抗肿瘤作用。
