Mittal S, Black P M
Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA.
Acta Neurochir Suppl. 2006;98:77-86. doi: 10.1007/978-3-211-33303-7_11.
The resection of brain tumors is limited by the surgeon's ability to precisely define margins. To overcome this problem, various neuronavigational tools have been used. The development of image-guided navigation systems represents a substantial improvement in the microsurgical treatment of various intracranial lesions. However, a major drawback of this technology is that they use images acquired preoperatively, on which the surgical planning and intraoperative performance is based. As the intracranial anatomy dynamically changes during a neurosurgical procedure, only intraoperatively acquired images can provide the neurosurgeon with the information needed to perform real-time, image-guided surgery. Because magnetic resonance imaging best delineates the soft-tissue extent of most tumors, it currently remains the superior method for intraoperative image guidance. In this review, we outline the development as well as current and possible future applications of the intraoperative MRI (iMRI) unit at the Brigham and Women's Hospital, Boston, MA.
脑肿瘤切除术受到外科医生精确界定边界能力的限制。为克服这一问题,人们使用了各种神经导航工具。图像引导导航系统的发展代表了各种颅内病变显微外科治疗的重大进步。然而,这项技术的一个主要缺点是它们使用术前获取的图像,手术规划和术中操作均基于这些图像。由于颅内解剖结构在神经外科手术过程中会动态变化,只有术中获取的图像才能为神经外科医生提供进行实时图像引导手术所需的信息。因为磁共振成像能最佳地描绘大多数肿瘤的软组织范围,所以它目前仍是术中图像引导的首选方法。在本综述中,我们概述了马萨诸塞州波士顿布里格姆妇女医院术中磁共振成像(iMRI)设备的发展以及当前和可能的未来应用。