Kazmierski Radoslaw
Poznan University of Medical Sciences, Department of Neurology, ul. Przybyszewskiego 49, 60-355 Poznan, Poland.
Expert Rev Neurother. 2006 Sep;6(9):1349-62. doi: 10.1586/14737175.6.9.1349.
Accurate predictors of early outcome in stroke patients have a number of important applications, such as introducing secondary prevention strategies, supporting treatment decisions or designing randomized clinical trials. Surprisingly, a generally accepted, reliable and well-validated mortality-prediction model is still unavailable. This review outlines the most important predictors of in-hospital mortality that could be assessed at admission to hospital emergency room within 24 h of ischemic stroke onset. A number of factors are discussed such as nonmodifiable factors (e.g., age, gender and genetic factors); type of stroke and its severity - measured by different clinical score scales; predictive models; laboratory markers; special neuroradiological and neurophysiological tests; and comorbid conditions at admission and quality of hospital care.
中风患者早期预后的准确预测指标有许多重要应用，比如引入二级预防策略、辅助治疗决策或设计随机临床试验。令人惊讶的是，目前仍没有一个被普遍接受、可靠且经过充分验证的死亡率预测模型。本综述概述了在缺血性中风发病24小时内入院至医院急诊室时可评估的最重要的院内死亡率预测指标。讨论了一些因素，如不可改变的因素（如年龄、性别和遗传因素）；中风类型及其严重程度——通过不同的临床评分量表衡量；预测模型；实验室指标；特殊的神经放射学和神经生理学检查；以及入院时的合并症和医院护理质量。
