Honda Kord S
Division of Dermatology, Box 356524, University of Washington School of Medicine, 1959 NE Pacific Street, Seattle, WA 98195, USA.
Dermatol Clin. 2006 Oct;24(4):521-30, vii. doi: 10.1016/j.det.2006.06.011.
AIDS produces profound alterations in normal immunity. Impaired cellular immunity permits new tumor formation as evidenced by the solid-organ transplant literature. The weakened cellular immune system of HIV-infected patients resembles in some ways the iatrogenic immunosuppression in solid-organ transplant recipients. This article summarizes what is known about skin cancer in the solid-organ transplant population and compares the immunodysregulation of HIV infection with the iatrogenic immunosuppression following solid-organ transplantation.
艾滋病会对正常免疫功能产生深刻改变。细胞免疫受损会导致新肿瘤形成，实体器官移植文献已有相关证据。HIV感染患者的细胞免疫系统减弱，在某些方面类似于实体器官移植受者的医源性免疫抑制。本文总结了实体器官移植人群中皮肤癌的已知情况，并比较了HIV感染导致的免疫失调与实体器官移植后的医源性免疫抑制。
