Manvikar Sridhar, Allen David
Sunderland Eye Infirmary, Sunderland, UK.
J Cataract Refract Surg. 2006 Oct;32(10):1611-4. doi: 10.1016/j.jcrs.2006.04.037.
To demonstrate a progressive approach to the problems of intraoperative floppy-iris syndrome (IFIS) in cataract surgery caused by tamsulosin.
Cataract Treatment Center, Sunderland Eye Infirmary, Sunderland, United Kingdom.
Thirty-two eyes of 20 patients who were using tamsulosin had cataract surgery by the same surgeon using the same technique. Patients received standard preoperative eyedrops consisting of topical cyclopentolate, phenylephrine, and diclofenac. When necessary, intracameral phenylephrine, iris hooks, or both were used. All cases were videotaped and analyzed for surgical complications.
The degree of IFIS manifested varied widely in the patients: Seventeen of 32 eyes (53%) had good mydriasis preoperatively (type 1 and type 2 pupils); however, in 7 of the 17 eyes (43%), the pupils constricted later during surgery (type 2 pupils). Twelve eyes (38%) had a mid-dilated pupil that sometimes constricted later (type 3 pupils), and 3 eyes (9%) had poor dilation at the beginning of surgery (type 4 pupils). There were no surgical complications attributed to IFIS. Full IFIS manifestation varied between eyes of the same patient. Some eyes required no intervention. Intraoperative pupil constriction was reversed with intracameral phenylephrine, which also prevented iris prolapse and billowing and further pupil constriction in patients who had medium to small pupils preoperatively.
A staged approach in managing pupils in IFIS and using phenylephrine intracamerally when necessary effectively prevented serious intraoperative complications.
展示一种针对坦索罗辛引起的白内障手术中虹膜松弛综合征(IFIS)问题的渐进式处理方法。
英国桑德兰市桑德兰眼科医院白内障治疗中心。
20例正在使用坦索罗辛的患者的32只眼由同一位外科医生采用相同技术进行白内障手术。患者术前接受标准眼药水,包括局部用环喷托酯、去氧肾上腺素和双氯芬酸。必要时,使用前房内去氧肾上腺素、虹膜钩或两者并用。所有病例均进行录像并分析手术并发症。
患者中IFIS的表现程度差异很大:32只眼中有17只(53%)术前瞳孔散大良好(1型和2型瞳孔);然而,这17只眼中有7只(43%)在手术后期瞳孔缩小(2型瞳孔)。12只眼(38%)瞳孔中度散大,有时后期会缩小(3型瞳孔),3只眼(9%)在手术开始时瞳孔散大不佳(4型瞳孔)。没有因IFIS导致的手术并发症。同一患者的不同眼睛之间IFIS的完全表现有所不同。一些眼睛无需干预。前房内注射去氧肾上腺素可逆转术中瞳孔缩小,这也可防止术前瞳孔中小的患者发生虹膜脱垂、飘动和进一步的瞳孔缩小。
对IFIS患者的瞳孔管理采用分阶段方法,并在必要时在前房内使用去氧肾上腺素,可有效预防严重的术中并发症。