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为什么女性和男性在滥用可卡因时会表现出如此大的差异呢? (注:原英文表述有误,正确的表达应该是“Why are women from Venus and men from Mars?(为什么女人来自金星,男人来自火星?)这里是在调侃男女之间的差异,结合语境推测是想问男女滥用可卡因时为何表现不同,所以翻译做了适当调整以使意思完整)

Why are women from Venus and men from Mars when they abuse cocaine?

作者信息

Quiñones-Jenab Vanya

机构信息

Department of Psychology, Hunter College and Graduate School, City University of New York, New York, NY 10021, USA.

出版信息

Brain Res. 2006 Dec 18;1126(1):200-3. doi: 10.1016/j.brainres.2006.08.109. Epub 2006 Sep 28.

Abstract

Both preclinical and clinical studies have shown sexually dimorphic patterns in behavioral responses to cocaine in all phases of the cocaine addiction process (induction, maintenance, and relapse). Thus, a clear picture is emerging which suggests that the biological basis of sex-specific differences in cocaine addiction resides in the disparate regulation of the CNS by male and female gonadal hormones. This review discusses the role that gonadal hormones play in these sexually dimorphic patterns of behavioral responses to cocaine.

摘要

临床前和临床研究均表明,在可卡因成瘾过程的各个阶段(诱导、维持和复发),对可卡因的行为反应存在性别差异模式。因此,一幅清晰的图景正在浮现,这表明可卡因成瘾中性别特异性差异的生物学基础在于男性和女性性腺激素对中枢神经系统的不同调节。本综述讨论了性腺激素在这些对可卡因行为反应的性别差异模式中所起的作用。

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