Christensen Helen, Low Lee-Fay, Anstey Kaarin J
Centre for Mental Health Research, The Australian National University, Canberra, Australia.
Curr Opin Psychiatry. 2006 Nov;19(6):587-92. doi: 10.1097/01.yco.0000245743.60631.4a.
This paper briefly outlines new research on the epidemiology of alcohol and drug use in the older population, describes mental and cognitive consequences of substance use and summarizes recent treatment trials for alcohol dependence.
Cross-sectional and longitudinal studies indicate that alcohol use is less prevalent in older groups, and it decreases over time. Comorbidity (alcohol and other drugs, alcohol with mental health disorders) is high. An inverse-U-shaped curve describes the association between alcohol consumption and cognitive impairment with increased impairment for abstainers and high users as compared with moderate users. Trials of alcohol use in the older population are rare, but they suggest that brief patient education may reduce drinking levels in primary care populations, and that, for some users, integrated primary care may be more useful than referral to specialist care.
The basis for higher risk in abstainers is not resolved. More randomized controlled trials are needed, which target alcohol use and dependence and also focus on comorbid disorders.
本文简要概述了老年人群酒精和药物使用流行病学的新研究,描述了物质使用的心理和认知后果,并总结了近期酒精依赖的治疗试验。
横断面研究和纵向研究表明,老年人群中酒精使用的普遍性较低,且随着时间推移呈下降趋势。共病情况(酒精与其他药物、酒精与精神健康障碍)较为常见。一条倒U形曲线描述了酒精消费与认知障碍之间的关联,与适度饮酒者相比,戒酒者和大量饮酒者的认知障碍有所增加。针对老年人群酒精使用的试验很少,但这些试验表明,简短的患者教育可能会降低初级保健人群的饮酒水平,而且对于一些使用者来说,综合初级保健可能比转诊至专科护理更有用。
戒酒者风险较高的原因尚未明确。需要更多针对酒精使用和依赖且关注共病障碍的随机对照试验。