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泰国僧侣膝关节骨关节炎的患病率、模式及危险因素

Prevalence, patterns, and risk factors of knee osteoarthritis in Thai monks.

作者信息

Tangtrakulwanich Boonsin, Geater Alan F, Chongsuvivatwong Virasakdi

机构信息

Department of Orthopaedic Surgery and Physical Medicine, Faculty of Medicine, Prince of Songkla University, Haadyai, Songkhla, 90110, Thailand.

出版信息

J Orthop Sci. 2006 Oct;11(5):439-45. doi: 10.1007/s00776-006-1040-y.

Abstract

BACKGROUND

Patterns and risk factors of knee osteoarthritis in Asian countries where most people have habitual knee bending activities remain unclear. The objective of this study was to evaluate the prevalence, patterns, and risk factors of knee osteoarthritis in Thai monks.

METHODS

The study was a cross-sectional survey of monks who lived in temples in southern Thailand. Investigations included history, physical examination, and radiographic evaluation including weight-bearing antero-posterior, lateral, and skyline views.

RESULTS

There were 261 monks from 85 temples included in this study. The overall prevalence of radiographic knee osteoarthritis was 59.4%, with 29.6% having symptomatic radiographic knee osteoarthritis. The patterns of involvement were isolated tibiofemoral compartment (7.7%), isolated patellofemoral compartment (18.8%), and combined (32.9%). Obesity (OR 5.6, 95% CI; 1.6-19.8), age equal to or more than 60 years (OR 3.0, 95% CI; 1.5-6.0), and age at ordainment equal to or more than 46 years (OR 2.2, 95% CI; 1.1-4.6) were associated with risk of developing radiographic knee osteoarthritis. Obesity (OR 17.9, 95% CI; 2.4-132.1) and current smoking (OR 7.7, 95% CI; 2.4-24.3) were associated with symptomatic radiographic knee osteoarthritis. Severity of involvement was associated with obesity (OR 12.0, 95% CI; 2.3-60.9), older age (OR 3.8, 95% CI; 1.3-5.1), and older age at ordainment (OR 2.8, 95% CI; 1.3-6.1).

CONCLUSIONS

The prevalence of radiographic knee osteoarthritis with patellofemoral involvement in Thai monks is high and is more common among the elderly, those who were older at ordainment, and obese subgroups. Each pattern of knee osteoarthritis might have a different pathomechanism in the development of osteoarthritis.

摘要

背景

在大多数人有习惯性屈膝活动的亚洲国家,膝关节骨关节炎的模式和危险因素尚不清楚。本研究的目的是评估泰国僧侣中膝关节骨关节炎的患病率、模式和危险因素。

方法

本研究是对居住在泰国南部寺庙中的僧侣进行的横断面调查。调查内容包括病史、体格检查和影像学评估,包括负重前后位、侧位和髌股关节切线位片。

结果

本研究纳入了来自85座寺庙的261名僧侣。膝关节影像学骨关节炎的总体患病率为59.4%,其中29.6%患有有症状的影像学膝关节骨关节炎。受累模式为单纯胫股关节间隙(7.7%)、单纯髌股关节间隙(18.8%)和混合型(32.9%)。肥胖(比值比5.6,95%置信区间;1.6 - 19.8)、年龄≥60岁(比值比3.0,95%置信区间;1.5 - 6.0)以及受戒年龄≥46岁(比值比2.2,95%置信区间;1.1 - 4.6)与影像学膝关节骨关节炎的发生风险相关。肥胖(比值比17.9,95%置信区间;2.4 - 132.1)和当前吸烟(比值比7.7,95%置信区间;2.4 - 24.3)与有症状的影像学膝关节骨关节炎相关。受累严重程度与肥胖(比值比12.0,95%置信区间;2.3 - 60.9)、年龄较大(比值比3.8,95%置信区间;1.3 - 5.1)以及受戒年龄较大(比值比2.8,95%置信区间;1.3 - 6.1)相关。

结论

泰国僧侣中髌股关节受累的影像学膝关节骨关节炎患病率较高,在老年人、受戒年龄较大者和肥胖亚组中更为常见。膝关节骨关节炎的每种模式在骨关节炎发展过程中可能有不同的发病机制。

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