Department of Rehabilitation Medicine, Seoul National University Bundang Hospital, Gumi-dong, Bundang-gu, Seongnam-si, Gyeonggi-do, Republic of Korea.
Arch Gerontol Geriatr. 2013 Mar-Apr;56(2):377-82. doi: 10.1016/j.archger.2012.10.013. Epub 2012 Nov 17.
The aim of the study is to compare factors associated with physical performance in older individuals with severe knee osteoarthritis and those with less-severe osteoarthritis. This is an ancillary cross-sectional study to a population-based cohort study focusing on Koreans age 65 years or older. The analysis included 553 subjects with information about knee pain, depressive symptoms, and comorbidities collected by self-reported questionnaire, and body weight, knee osteoarthritis severity, muscle strength, and physical measures by observer-rated tests. Stepwise logistic regression analyses were performed with physical performance as an outcome variable and the others as independent variables across radiographic knee osteoarthritis severity. In the minimal-to-moderate-severity group, muscle strength, knee pain, BMI, and age were related to poor performance (OR [CI] 0.81 [0.73-0.90], 1.12 [1.03-1.21], 0.87 [0.79-0.96], and 1.09 [1.05-1.14], respectively). In the severe group, muscle strength was the only factor significantly associated with poor performance (OR [CI] 0.72 [0.58-0.89]). Muscle strength, knee pain, and BMI were important determinants of physical performance in the older population with knee osteoarthritis. In severe knee osteoarthritis patients, muscle strength was the only significant determinant.
本研究旨在比较严重膝骨关节炎和轻度膝骨关节炎老年患者的身体机能相关因素。这是一项基于人群的队列研究的辅助横断面研究，研究对象为 65 岁及以上的韩国人。分析纳入了 553 名受试者，通过自填问卷收集了有关膝关节疼痛、抑郁症状和合并症的信息，并通过观察者评估的测试收集了体重、膝骨关节炎严重程度、肌肉力量和身体测量值。对各严重程度的膝关节放射影像进行逐步逻辑回归分析，以身体机能为因变量，其他因素为自变量。在轻度至中度严重组中，肌肉力量、膝关节疼痛、BMI 和年龄与较差的表现相关（OR [CI] 0.81 [0.73-0.90]、1.12 [1.03-1.21]、0.87 [0.79-0.96]和 1.09 [1.05-1.14]）。在严重组中，肌肉力量是唯一与较差表现显著相关的因素（OR [CI] 0.72 [0.58-0.89]）。肌肉力量、膝关节疼痛和 BMI 是老年膝骨关节炎患者身体机能的重要决定因素。在严重膝骨关节炎患者中，肌肉力量是唯一的显著决定因素。
