Hardy John
Laboratory of Neurogenetics, National Institute on Aging, Porter Neuroscience Building, Bethesda, Maryland 20892, USA.
Neuron. 2006 Oct 5;52(1):3-13. doi: 10.1016/j.neuron.2006.09.016.
On the 100th anniversary of Alzheimer's lecture describing the clinicopathological entity which bears his eponym, this article reviews the major areas of progress in our understanding of the disease and outlines the many gaps still remaining. The progress toward effective mechanistic therapy is reviewed.
在那场描述了以其名字命名的临床病理实体的阿尔茨海默病讲座举办100周年之际,本文回顾了我们对该疾病理解方面取得重大进展的主要领域,并概述了仍然存在的诸多空白。同时还回顾了在有效机制性治疗方面取得的进展。