Lieb W E, Shields J A, Eagle R C, Kwa D, Shields C L
Wills Eye Hospital, Jefferson Medical College, Thomas Jefferson University, Philadelphia, PA 19107.
Ophthalmology. 1990 Nov;97(11):1489-93. doi: 10.1016/s0161-6420(90)32375-8.
A 51-year-old white man was found to have a deeply pigmented mass in the ciliary body and peripheral choroid of his right eye with an associated vitreous hemorrhage. Although the tumor appeared to be a ciliochoroidal melanoma, a melanocytoma and adenoma of the pigment epithelium also were considered in the differential diagnosis. The tumor was removed by a large partial lamellar sclerocyclochoroidectomy. Results of histopathologic evaluation showed a cystic adenoma of the pigmented ciliary epithelium. To the authors' knowledge, this was the first immunohistopathologic study of this tumor. Results of the study showed marked immunoreactivity for low molecular weight cytokeratins, vimentin, and S-100 protein. These immunohistochemical studies are consistent with the origin of this tumor from pigment epithelial cells.
一名51岁的白人男性被发现右眼睫状体和周边脉络膜有一个色素沉着很深的肿块，并伴有玻璃体积血。尽管该肿瘤看似是睫状体脉络膜黑色素瘤，但在鉴别诊断中也考虑了色素细胞瘤和色素上皮腺瘤。通过大范围部分板层巩膜睫状体脉络膜切除术切除了肿瘤。组织病理学评估结果显示为色素性睫状体上皮的囊性腺瘤。据作者所知，这是对该肿瘤的首次免疫组织病理学研究。研究结果显示对低分子量细胞角蛋白、波形蛋白和S-100蛋白有明显的免疫反应性。这些免疫组织化学研究结果与该肿瘤起源于色素上皮细胞一致。
