Lloyd Charmaine A C, Jacob Swarna E, Menon Thangam
Department of Microbiology, Dr A L Mudaliar Post Graduate Institute of Basic Medical Sciences Chennai, India.
Indian J Med Res. 2006 Aug;124(2):195-8.
BACKGROUND & OBJECTIVES: Asymptomatic pharyngeal carriage of group A streptococci (GAS) in children may lead to spread of respiratory infections in the community. Data on healthy GAS carriers in the community are therefore important. We carried out this preliminary study to screen the school children from various parts of Chennai city, south India to detect pharyngeal carriage of GAS.
Throat swabs were collected from 1,173 school children aged 5 to 17 yr from different locations in Chennai. The isolates of beta haemolytic streptococci were serogrouped by agglutination tests using specific antisera.
Beta haemolytic streptococci were isolated from 16.3 per cent of 1,102 asymptomatic children. 71 children of the study group had untreated tonsillitis positive for beta haemolytic streptococci. The percentage of asymptomatic GAS carriers was 8.4 per cent.
INTERPRETATION & CONCLUSION: The high carriage rate of beta haemolytic streptococci seen in children poses a threat to the community and should be checked. Regular screening needs to be done in various parts of the country.
儿童中A组链球菌（GAS）的无症状咽部携带可能导致社区呼吸道感染的传播。因此，关于社区中健康GAS携带者的数据很重要。我们开展了这项初步研究，以筛查印度南部钦奈市不同地区的学童，检测GAS的咽部携带情况。
从钦奈不同地点的1173名5至17岁学童中采集咽拭子。使用特定抗血清通过凝集试验对β溶血性链球菌分离株进行血清分组。
在1102名无症状儿童中，16.3%分离出β溶血性链球菌。研究组中有71名儿童患有未经治疗的扁桃体炎，β溶血性链球菌呈阳性。无症状GAS携带者的比例为8.4%。
儿童中β溶血性链球菌的高携带率对社区构成威胁，应予以控制。需要在该国各地定期进行筛查。
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