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[青光眼手术后晚期失败滤过泡的针刺修复]

[Needle revision of late failing filtering blebs after glaucoma surgery].

作者信息

Perucho-Martínez S, Gutiérrez-Díaz E, Montero-Rodríguez M, Mencía-Gutiérrez E, Lago-Llinás M D

机构信息

Servicio de Oftalmología, Hospital Universitario 12 de Octubre, C/Cabo San Vicente 10, 28924 Madrid, Spain.

出版信息

Arch Soc Esp Oftalmol. 2006 Sep;81(9):517-22. doi: 10.4321/s0365-66912006000900006.

DOI:10.4321/s0365-66912006000900006
PMID:17016783
Abstract

PURPOSE

To evaluate the results of bleb needling in eyes subjected to filtering surgery six months or more previously.

METHODS

A retrospective study of 23 eyes in 21 patients subjected to bleb needling performed by means of a 25G needle, 6 months to 23 years after failed filtering surgery (mean 67.3 months). The mean number of bleb needlings was 1.2 and the mean number of 5-fluorouracil subconjunctival injections was 3.9.

RESULTS

The mean intraocular pressure (IOP) before needling was 26 mmHg and the mean anti-glaucoma medications was 1.3 per eye. The mean postoperative IOP was 16.3 mmHg and mean anti-glaucoma medications 0.7. A diffuse filtering bleb was evident in 12 eyes (54.5%). The results of needling were worse in eyes subjected to previous surgery for glaucoma or other failed bleb needling procedures (75% failure).

CONCLUSION

Needle revision of the filtering bleb is a simple and safe technique that offers good results even years after a filtering surgery had been performed. It should be considered before other medical or surgical treatments in patients with a previously functioning bleb and a permeable sclerectomy site at gonioscopy.

摘要

目的

评估对6个月或更久之前接受过滤过手术的眼睛进行滤泡针刺的效果。

方法

对21例患者的23只眼睛进行回顾性研究,这些眼睛在滤过手术失败6个月至23年后(平均67.3个月)接受了25G针头的滤泡针刺。滤泡针刺的平均次数为1.2次,结膜下注射5-氟尿嘧啶的平均次数为3.9次。

结果

针刺前平均眼压(IOP)为26 mmHg,每只眼睛平均使用抗青光眼药物1.3种。术后平均眼压为16.3 mmHg,平均抗青光眼药物为0.7种。12只眼睛(54.5%)出现弥漫性滤过泡。既往接受过青光眼手术或其他滤泡针刺失败手术的眼睛针刺效果较差(失败率75%)。

结论

滤过泡针刺修复是一种简单安全的技术,即使在滤过手术后数年也能取得良好效果。对于既往滤过泡功能良好且房角镜检查显示巩膜切除部位可通透的患者,在进行其他药物或手术治疗之前应考虑该方法。

相似文献

1
[Needle revision of late failing filtering blebs after glaucoma surgery].[青光眼手术后晚期失败滤过泡的针刺修复]
Arch Soc Esp Oftalmol. 2006 Sep;81(9):517-22. doi: 10.4321/s0365-66912006000900006.
2
[Late needling with 5-fluorouracil when scarring of filtering bleb seems imminent].[当滤过泡瘢痕形成似乎即将发生时,晚期联合使用5-氟尿嘧啶进行针刺治疗]
Ophthalmologe. 2007 Apr;104(4):305-10. doi: 10.1007/s00347-007-1497-x.
3
Single needle revision of failing filtration blebs: a retrospective comparative case series with 5-fluorouracil and mitomycin C.失败滤过泡的单针修复:5-氟尿嘧啶与丝裂霉素C的回顾性比较病例系列研究
Eur J Ophthalmol. 2010 Nov-Dec;20(6):1026-34. doi: 10.1177/112067211002000624.
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Needle Revision With 5-fluorouracil for the Treatment of Ahmed Glaucoma Valve Filtering Blebs: 5-Fluoruracil Needling Revision can be a Useful and Safe Tool in the Management of Failing Ahmed Glaucoma Valve Filtering Blebs.使用5-氟尿嘧啶进行针刺修复治疗艾哈迈德青光眼阀滤过泡:5-氟尿嘧啶针刺修复可能是处理失败的艾哈迈德青光眼阀滤过泡的一种有用且安全的方法。
J Glaucoma. 2016 Apr;25(4):e367-71. doi: 10.1097/IJG.0000000000000366.
5
Surgical repair of leaking filtering blebs.渗漏性滤过泡的手术修复
Ophthalmology. 2000 Sep;107(9):1681-7. doi: 10.1016/s0161-6420(00)00282-7.
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Office-based slit-lamp needle revision with adjunctive mitomycin-C for late failed or encapsulated filtering blebs.采用辅助丝裂霉素C的门诊裂隙灯针修复术治疗晚期失败或包裹性滤过泡。
Middle East Afr J Ophthalmol. 2012 Apr-Jun;19(2):216-21. doi: 10.4103/0974-9233.95255.
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5-Fluorouracil-needling and paracentesis through the failing filtering bleb.5-氟尿嘧啶经失败滤过泡针刺及腹腔穿刺术
Ophthalmic Surg Lasers. 2002 Mar-Apr;33(2):109-16.
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The role of needle revision and 5-fluorouracil application over the filtration site in the management of bleb failure after trabeculectomy: a prospective study.小梁切除术后滤过泡失败处理中滤过部位针拨与应用5-氟尿嘧啶的作用:一项前瞻性研究
Doc Ophthalmol. 2003 Mar;106(2):189-93. doi: 10.1023/a:1022550125261.
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The efficacy of 5-fluorouracil bleb needling performed 1 year or more posttrabeculectomy: a retrospective study.小梁切除术后1年或更长时间进行5-氟尿嘧啶泡内注射的疗效:一项回顾性研究
J Glaucoma. 2009 Feb;18(2):144-8. doi: 10.1097/IJG.0b013e318170a71c.
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Comparison of needle revision with subconjunctival bevacizumab and 5-fluorouracil injection of failed trabeculectomy blebs.比较失败的小梁切除术后滤过泡针拨术与结膜下贝伐单抗和 5-氟尿嘧啶注射。
J Ocul Pharmacol Ther. 2012 Oct;28(5):542-6. doi: 10.1089/jop.2012.0035. Epub 2012 Jun 25.

引用本文的文献

1
Early transconjunctival needling revision with 5-fluorouracil versus medical treatment in encapsulated blebs: a 12-month prospective study.早期经结膜巩膜穿刺联合 5-氟尿嘧啶与药物治疗在囊泡性滤过泡中的应用:一项 12 个月前瞻性研究。
Clinics (Sao Paulo). 2013 Oct;68(10):1376-9. doi: 10.6061/clinics/2013(10)14.
2
Efficacy of repeated 5-fluorouracil needling for failing and failed filtering surgeries based on simple gonioscopic examination.基于单纯前房角镜检查,重复5-氟尿嘧啶针刺术治疗滤过手术失败和已失败病例的疗效。
Clin Ophthalmol. 2013;7:15-22. doi: 10.2147/OPTH.S34848. Epub 2012 Dec 28.
3
Mitomycin-C needle bleb revision in congenital glaucoma.
丝裂霉素C针剂用于先天性青光眼的滤泡修复
Middle East Afr J Ophthalmol. 2010 Oct;17(4):369-73. doi: 10.4103/0974-9233.71598.