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[无ST段抬高的急性冠状动脉缺血综合征。糖蛋白IIB/IIIA抑制剂和经皮冠状动脉介入治疗的作用]

[Acute coronary ischemic syndrome without ST elevation. Role of glycoprotein IIB/IIIA inhibitors and percutaneous coronary interventions].

作者信息

Peña Duque Marco Antonio

机构信息

Departamento de Hemodinámica, Instituto Nacional de Cardiología Ignacio Chávez, Tlalpan, DF México.

出版信息

Arch Cardiol Mex. 2006 Apr-Jun;76 Suppl 2:S249-51.

PMID:17017111
Abstract

Myocardial infarction without ST elevation and unstable angina, represents a diagnostic challenge. This Syndromes are caused by rupture of a vulnerable plaque which determines intraluminal thrombosis, distal embolism and coronary obstruction. Administration of IIb/IIIa inhibitors produces some benefits, mainly in those patients who are taking to catheterization. Coronary intervention based on a routine invasive strategy, has decreased major cardiac events principally at long term.

摘要

非ST段抬高型心肌梗死和不稳定型心绞痛是诊断难题。这些综合征由易损斑块破裂引起,导致管腔内血栓形成、远端栓塞和冠状动脉阻塞。使用IIb/IIIa抑制剂有一定益处,主要体现在接受导管插入术的患者中。基于常规侵入性策略的冠状动脉介入治疗主要在长期降低了主要心脏事件的发生率。

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