Skoczylas Aleksander
Oddziału Wewnetrznego Szpitala Powiatowego w Oleśnie.
Wiad Lek. 2006;59(5-6):403-6.
The increase in the prevalence of obesity is associated with an increased risk of the development of cardiovascular and renal diseases. Extensive epidemiological studies have demonstrated a relation between the body weight rate and the blood pressure, indicating obesity as one of the factors in hypertension development. Some classes of antihypertensive drugs have potentially adverse effects on some of the metabolic abnormalities that link obesity and hypertension. At the same time, there is no scientific evidence indicating a more efficient group of drugs in the pharmacological management of the obese-related hypertension, therefore the drug treatment choice is based on experience and observations. Based on a particular mechanism leading to the development of hypertension in the obese individuals, the treatment includes the weight reduction associated with the pharmacological management which decreases the risks of both hypertension and obesity.
肥胖患病率的增加与心血管疾病和肾脏疾病发生风险的增加相关。广泛的流行病学研究已证实体重率与血压之间存在关联,表明肥胖是高血压发病的因素之一。某些类别的抗高血压药物对一些将肥胖与高血压联系起来的代谢异常可能有不良影响。同时,没有科学证据表明在肥胖相关高血压的药物治疗中哪一组药物更有效,因此药物治疗的选择基于经验和观察。基于导致肥胖个体发生高血压的特定机制,治疗包括与药物治疗相结合的体重减轻,这可降低高血压和肥胖的风险。