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[肛门直肠畸形患儿的神经膀胱功能障碍]

[Neurovesical dysfunction in children with anorectal malformations].

作者信息

Bán Gyula, Németh Péter, Túri Sándor

机构信息

Szent-Györgyi Albert Orvos- és Gyógyszerésztudományi Centrum, Altalános Orvostudományi Kar, Gyermekgyógyászati Klinika, Szeged.

出版信息

Orv Hetil. 2006 Aug 27;147(34):1645-9.

Abstract

Chronic renal failure remain the most significant cause of morbidity and mortality in patients with anorectal malformation. The urological anomalies associated with anorectal malformations are not only anatomical, but also functional, the latter being related to congenital neurovesical dysfunction. The neurovesical dysfunction found in children with anorectal malformations results from a possible association with spinal dysraphism. The authors carried out urodynamic evaluation on 6 patients operated on for anorectal malformation by posterior sagittal anorectoplasty. 3 children had normal bladder function, but 3 had neurovesical dysfunction (1 unstable bladder, 2 neuropathic bladder). It is concluded that in patients with anorectal malformations urodynamic investigations should be performed as a routine investigation of the urinary tract. Consequently, patients with lower urinary tract dysfunction should receive prompt treatment, including clean intermittent catheterization, to prevent or reduce secondary urologic morbidity, especially loss of renal function.

摘要

慢性肾衰竭仍然是肛门直肠畸形患者发病和死亡的最主要原因。与肛门直肠畸形相关的泌尿系统异常不仅涉及解剖结构,还包括功能方面,后者与先天性神经膀胱功能障碍有关。在患有肛门直肠畸形的儿童中发现的神经膀胱功能障碍可能与脊柱裂有关。作者对6例接受后矢状位肛门直肠成形术治疗肛门直肠畸形的患者进行了尿动力学评估。3名儿童膀胱功能正常,但3名存在神经膀胱功能障碍(1例膀胱不稳定,2例神经源性膀胱)。得出的结论是,对于肛门直肠畸形患者,应将尿动力学检查作为泌尿系统的常规检查。因此,下尿路功能障碍的患者应及时接受治疗,包括清洁间歇性导尿,以预防或减少继发性泌尿系统疾病,尤其是肾功能丧失。

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