Magloire Lissa K, Pettker Christian M, Buhimschi Catalin S, Funai Edmund F
Department of Obstetrics, Gynecology & Reproductive Sciences, Yale University School of Medicine, New Haven, CT 06520, USA.
Obstet Gynecol. 2006 Sep;108(3 Pt 2):743-5. doi: 10.1097/01.AOG.0000189719.36625.8f.
Burkitt's lymphoma is a rapidly growing and, if untreated, rapidly fatal tumor derived from B-lymphocytes. The occurrence of Burkitt's lymphoma during pregnancy is rare.
A patient with Burkitt's lymphoma presented at 12 weeks of gestation with abdominal and tooth pain. An 11 x 11 x 15 cm mass was seen on abdominal/pelvic ultrasonogram. She underwent a left salpingo-oophorectomy with removal of the mass, as well as a tooth extraction. The pathology examination confirmed lymphoma in the left ovary and in the tissue surrounding the extracted tooth. After surgical resection, she was treated with multiagent chemotherapy beginning at 13 4/7 weeks of gestation. At 39 weeks, she delivered a viable female infant weighing 2,270 g.
The finding of an adnexal mass in conjunction with head and neck symptoms led to consideration of Burkitt's lymphoma. Prompt treatment with multiagent chemotherapy should be considered for pregnant patients with Burkitt's lymphoma.
伯基特淋巴瘤是一种快速生长的肿瘤,若不治疗会迅速致命,它起源于B淋巴细胞。孕期发生伯基特淋巴瘤的情况较为罕见。
一名患有伯基特淋巴瘤的患者在妊娠12周时出现腹痛和牙痛。腹部/盆腔超声检查发现一个11×11×15厘米的肿块。她接受了左侧输卵管卵巢切除术并切除肿块,同时拔除了一颗牙齿。病理检查证实左侧卵巢和拔除牙齿周围组织存在淋巴瘤。手术切除后,她在妊娠13又4/7周开始接受多药联合化疗。孕39周时,她产下一名体重2270克的存活女婴。
附件肿块伴有头颈部症状提示考虑伯基特淋巴瘤。对于患有伯基特淋巴瘤的孕妇,应考虑及时进行多药联合化疗。