日本人红细胞尿苷单磷酸激酶的多态性

Red cell uridine monophosphate kinase polymorphism in Japanese.

作者信息

Harada S, Ito M, Misawa S

出版信息

Humangenetik. 1975 Sep 23;29(3):255-7. doi: 10.1007/BF00297632.

DOI:10.1007/BF00297632

Abstract

Samples from 635 unrelated Japanese blood doners in Tokyo were examined for their red cell uridine monophosphate kinase phenotypes using starch gel electrophoresis. Three phenotypes were found: UMPK1 (570, 89.76%), UMPK 2--1 (63, 9.92%) and UMPK 2 (2, 0.32%). The corresponding gene frequency for UMPK1 was 0.9472 and for UMPK2 was 0.0528. The UMPK2 frequency in the present study was slightly higher than the previously reported value for Caucasians in the United States, but the difference is not statistically significant. A study of 15 twin pairs and their parents was in agreement with the hypothesis of autosomal codominant inheritance for UMPK.

摘要

利用淀粉凝胶电泳，对东京635名无亲缘关系的日本献血者的样本进行了红细胞尿苷单磷酸激酶表型检测。发现了三种表型：UMPK1（570例，占89.76%）、UMPK 2--1（63例，占9.92%）和UMPK 2（2例，占0.32%）。UMPK1的相应基因频率为0.9472，UMPK2的相应基因频率为0.0528。本研究中UMPK2的频率略高于此前报道的美国白种人的频率，但差异无统计学意义。对15对双胞胎及其父母的研究结果与UMPK的常染色体共显性遗传假说相符。

相似文献

1

Red cell uridine monophosphate kinase polymorphism in Japanese.日本人红细胞尿苷单磷酸激酶的多态性

Humangenetik. 1975 Sep 23;29(3):255-7. doi: 10.1007/BF00297632.

2

Red cell uridine monophosphate kinase: effects of red cell aging on the activity of two UMPK gene products.红细胞尿苷单磷酸激酶：红细胞衰老对两种UMPK基因产物活性的影响。

Am J Hum Genet. 1976 Mar;28(2):138-42.

3

Red-cell uridine-5-monophosphate kinase (UMPK): formal genetics, linkage analysis and population genetics from southwestern Germany.红细胞尿苷-5-单磷酸激酶（UMPK）：来自德国西南部的正式遗传学、连锁分析和群体遗传学

Humangenetik. 1975 Jul 23;28(3):255-8. doi: 10.1007/BF00278554.

4

Red cell uridine monophosphate kinase (UMPK) and glyoxalase I (GLO) polymorphisms in a Japanese population: with a description of the new phenotype UMPK 4--1.日本人群中红细胞尿苷单磷酸激酶（UMPK）和乙二醛酶I（GLO）的多态性：兼述新表型UMPK 4--1

Bull Osaka Med Sch. 1977 Oct;23(2):63-6.

5

The polymorphism of red cell uridine monophosphate kinase in two samples of the Italian population.意大利人群两个样本中红细胞尿苷单磷酸激酶的多态性

Hum Hered. 1977;27(5):332-5. doi: 10.1159/000152887.

6

Uridine monophosphate kinase polymorphism in two Venezuelan populations.委内瑞拉两个群体中的尿苷单磷酸激酶多态性

Am J Hum Genet. 1978 Mar;30(2):215-8.

7

Biochemical characterization of a red cell UMP kinase variant found in the Warao indians of Venezuela.委内瑞拉瓦劳印第安人中发现的一种红细胞UMP激酶变体的生化特性

Biochem Genet. 1978 Dec;16(11-12):1085-92. doi: 10.1007/BF00484529.

8

UMPK polymorphism in the Polish population.波兰人群中的UMPK基因多态性

Arch Immunol Ther Exp (Warsz). 1985;33(5):621-4.

9

Genetic analysis of erythrocyte uridine monophosphate kinase and aminolevulinate dehydrase and its application to paternity testing.红细胞尿苷单磷酸激酶和氨基乙酰丙酸脱水酶的基因分析及其在亲子鉴定中的应用。

J Forensic Sci. 1989 Sep;34(5):1090-4.

10

A comparative study of the age-related patterns of decay of some nucleoside monophosphate kinases in human red cells.人红细胞中某些核苷单磷酸激酶衰老相关衰变模式的比较研究。

Biochem Genet. 1978 Dec;16(11-12):1219-32. doi: 10.1007/BF00484542.

引用本文的文献

1

Polymorphism of uridine monophosphate kinase: population study in Japanese and phenotyping in bloodstains.尿苷单磷酸激酶的多态性：日本人的群体研究及血迹中的表型分析

Int J Legal Med. 1990 Dec;104(1):13-6. doi: 10.1007/BF01816477.

2

Gene frequencies of red-cell uridine-5-monophosphate kinase (UMPK) in Western Germany (Düsseldorf region).西德（杜塞尔多夫地区）红细胞尿苷-5-单磷酸激酶（UMPK）的基因频率

Z Rechtsmed. 1982;88(1-2):93-5. doi: 10.1007/BF00200740.

3

Population genetic studies of the Philippine Negritos. I. A pilot survey of red cell enzyme and serum protein groups.菲律宾尼格利陀人的群体遗传学研究。I. 红细胞酶和血清蛋白组的初步调查。

Am J Hum Genet. 1978 Mar;30(2):190-201.

4

Uridine monophosphate kinase polymorphism in two Venezuelan populations.委内瑞拉两个群体中的尿苷单磷酸激酶多态性

Am J Hum Genet. 1978 Mar;30(2):215-8.

本文引用的文献

1

Uridine monophosphate kinase: A new genetic polymorphism with possible clinical implications.尿苷单磷酸激酶：一种具有潜在临床意义的新基因多态性。

Am J Hum Genet. 1974 Sep;26(5):627-35.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

文档翻译

学术文献翻译模型，支持多种主流文档格式。