Serov Alexander N, Nieland Janharm, Oosterbaan Sjoerd, de Mul Frits F M, van Kranenburg Herma, Bekman Herman H P T, Steenbergen Wiendelt
University of Twente, 7500 AE Enschede, The Netherlands.
IEEE Trans Biomed Eng. 2006 Oct;53(10):2067-74. doi: 10.1109/TBME.2006.877106.
An integrated optoelectronic probe with small dimensions, for direct-contact laser Doppler blood flow monitoring has been realized. A vertical cavity surface emitting laser (VCSEL), and a chip with photodetectors and all necessary electronics are integrated in a miniature probe head connected to a laptop computer. The computer sound processor is utilized for acquisition and digital signal processing of the incoming Doppler signal. In this paper, the design of the laser Doppler perfusion monitor is described and its performance is evaluated. We demonstrate our perfusion monitor to be less sensitive to subject motion than a commercial fiber-optic device. For medium and high perfusion levels, the performance of our integrated probe is comparable to the fiberoptic flowmeter containing a normal edge-emitting laser diode. For very low perfusion levels, the signal-to-noise ratio of the fiber-optic device is higher. This difference can mainly be attributed to the shorter coherence length of the VCSEL compared with the edge-emitting laser diode.
一种用于直接接触式激光多普勒血流监测的小尺寸集成光电探头已被实现。一个垂直腔面发射激光器（VCSEL）以及一个带有光电探测器和所有必要电子元件的芯片被集成在一个连接到笔记本电脑的微型探头中。计算机声音处理器用于采集和数字信号处理传入的多普勒信号。本文描述了激光多普勒灌注监测仪的设计并评估了其性能。我们证明我们的灌注监测仪对受试者运动的敏感度低于商用光纤设备。对于中高灌注水平，我们集成探头的性能与包含普通边发射激光二极管的光纤流量计相当。对于非常低的灌注水平，光纤设备的信噪比更高。这种差异主要可归因于与边发射激光二极管相比，VCSEL的相干长度更短。
