Kubicka-Trzaska Agnieszka, Romanowska-Dixon Bozena
Katedry i Kliniki Okulistyki Collegium Medicum, Uniwersytetu Jagiellońskiego w Krakowie.
Klin Oczna. 2006;108(4-6):206-8.
To present a clinical picture and results of treatment in two patients with bronchial carcinoid metastases to choroid.
Two females aged 47 and 56 with bilateral and multiple metastases of bronchial carcinoid were enrolled in this study. Choroidal metastases occurred 6-7 years after primary tumors had been diagnosed. The follow-up period ranged from 2.5 to 5 years. In one patient teleradiotherapy of choroidal metastases was performed, while in a second case plaque therapy with 106 Ru and 125 I and a diode laser therapy were used.
After therapy, one patient demonstrated partial regression of two choroidal metastases and total regression of one tumor, while the second one, showed total regression of all intraocular tumors. One patient developed irradiation neuropathy and retinopathy as a result of teleradiotherapy, which were the main cause of decreased visual acuity in her one eye.
Regarding the good prognosis and potentially long survival of patients with bronchial carcinoid, prompt treatment of choroidal metastases is recommended. Applied method of therapy depends on tumor size, its localization and patient's general condition.
介绍两例支气管类癌转移至脉络膜患者的临床表现及治疗结果。
本研究纳入了两名分别为47岁和56岁的女性患者，她们均患有双侧多发性支气管类癌转移。脉络膜转移发生在原发性肿瘤确诊后的6 - 7年。随访期为2.5至5年。其中一名患者接受了脉络膜转移灶的远距离放射治疗，而另一名患者则采用了106钌和125碘敷贴治疗以及二极管激光治疗。
治疗后，一名患者的两个脉络膜转移灶部分消退，一个肿瘤完全消退，而另一名患者的所有眼内肿瘤完全消退。一名患者因远距离放射治疗出现了放射性神经病变和视网膜病变，这是其一只眼睛视力下降的主要原因。
鉴于支气管类癌患者预后良好且可能长期存活，建议对脉络膜转移灶进行及时治疗。所采用的治疗方法取决于肿瘤大小、其位置以及患者的一般状况。
