Gryko Daniel T, Piechowska Joanna, Tasior Mariusz, Waluk Jacek, Orzanowska Grazyna
Institute of Organic Chemistry of the Polish Academy of Sciences, Kasprzaka 44/52, 01-224 Warsaw, Poland.
Org Lett. 2006 Oct 12;8(21):4747-50. doi: 10.1021/ol061827m.
[structure: see text] An unexpected discovery of a novel cyclocondensation reaction of 1,8-diazabicyclo[5.4.0]undec-8-ene (DBU) with activated 1,2-dichloro compounds is described. The 2-aminopyrrole skeleton is generated through the concomitant formation of new nitrogen-carbon and carbon-carbon bonds. A new pentacyclic derivative formed upon the reaction of 2,3-dichloroquinoxaline with DBU exhibits strong fluorescence both in solutions (Phi in hexane = 0.4) and in the solid state.
[结构：见正文] 本文描述了1,8-二氮杂双环[5.4.0]十一碳-8-烯（DBU）与活性1,2-二氯化合物发生的一种新型环缩合反应这一意外发现。2-氨基吡咯骨架是通过同时形成新的氮-碳键和碳-碳键而产生的。2,3-二氯喹喔啉与DBU反应生成的一种新的五环衍生物在溶液（在己烷中的Φ = 0.4）和固态下均表现出强荧光。
