Buck Deborah, Hatt Sarah R, Haggerty Helen, Hrisos Susan, Strong Nicholas P, Steen Nicholas I, Clarke Michael P
Institute of Health and Society, Newcastle University, Newcastle upon Tyne, UK.
Br J Ophthalmol. 2007 Feb;91(2):215-8. doi: 10.1136/bjo.2006.097790. Epub 2006 Oct 4.
To evaluate the use of the Newcastle Control Score (NCS) in the management of intermittent exotropia (X(T)).
Children aged <11 years with X(T) had an assessment of NCS as part of routine management. Other data collected included visual acuity, near and distance alignment with alternating prism cover test and near (Frisby test) and distance stereoacuity (Frisby Davis Distance Stereotest (FD2TM)). Analysis involved correlation between baseline NCS, angle and stereoacuity, examination of change over time and logistic regression to determine predictors of surgery.
Baseline data were obtained on 272 children and follow-up data on 157. Mean (SD) age was 4 (1.9) years. Complete NCSs were obtained for all except one child at baseline, and all children at follow-up. At baseline, total NCS and the home control component were correlated with near stereo (r = -0.22, p<0.01 and r = -0.19, p<0.02, respectively), near alignment (r = 0.34, p<0.001 and r = 0.19, p<0.02) and distance alignment (r = 0.30, p<0.001 and r = 0.26, p<0.001). The clinic near control component was correlated with near alignment (r = 0.39, p<0.001), but not near stereoacuity, and the clinic distance control with near alignment (r = 0.16, p<0.02), distance alignment (r = 0.27, p<0.001) and distance stereoacuity (r = -0.25, p<0.03). A high (poor) NCS (> or =4) at the latest follow-up predicted surgery (p<0.001, OR 29.3, 95% CI 6.2 to 138.7).
The NCS is a useful measure of the clinical severity of X(T), can be used to serially assess improvement or deterioration and is a useful tool for the management of these patients.
评估纽卡斯尔控制评分（NCS）在间歇性外斜视（X(T)）管理中的应用。
年龄小于11岁的X(T)患儿在常规管理中接受NCS评估。收集的其他数据包括视力、交替棱镜遮盖试验的近距和远距眼位矫正情况以及近距（弗里斯比试验）和远距立体视锐度（弗里斯比戴维斯远距立体视测试（FD2TM））。分析包括基线NCS、斜视角度和立体视锐度之间的相关性，随时间变化的检查以及确定手术预测因素的逻辑回归分析。
获取了272名儿童的基线数据以及157名儿童的随访数据。平均（标准差）年龄为4（1.9）岁。除一名儿童外，所有儿童在基线时均获得了完整的NCS，随访时所有儿童均获得完整NCS。在基线时，总NCS和家庭控制部分与近距立体视（分别为r = -0.22，p<0.01和r = -0.19，p<0.02）、近距眼位矫正（r = 0.34，p<0.001和r = 0.19，p<0.02）以及远距眼位矫正（r = 0.30，p<0.001和r = 0.26，p<0.001）相关。门诊近距控制部分与近距眼位矫正（r = 0.39，p<0.001）相关，但与近距立体视锐度无关，门诊远距控制与近距眼位矫正（r = 0.16，p<0.02）、远距眼位矫正（r = 0.27，p<0.001）和远距立体视锐度（r = -0.25，p<0.03）相关。最新随访时高（差）NCS（≥4）预测手术（p<0.001，OR 29.3，95%CI 6.2至138.7）。
NCS是衡量X(T)临床严重程度的有用指标，可用于连续评估病情改善或恶化情况，是管理这些患者的有用工具。
