Bartolotta T V, Midiri M, Runza G, Galia M, Taibbi A, Damiani L, Palermo Patera G, Lagalla R
Sezione di Diagnostica per Immagini, Dipartimento di Biotecnologie Mediche e Medicina Legale, Policlinico Universitario, Via del Vespro 127, I-90127 Palermo, Italy.
Radiol Med. 2006 Oct;111(7):989-98. doi: 10.1007/s11547-006-0097-1. Epub 2006 Oct 11.
Our aim was to assess the incidence and ultrasound features of thyroid nodules in an adult population screened by means of high-resolution ultrasonography (HRUS) and to evaluate the contribution of real-time spatial compound sonography (CS) in terms of image quality.
A total of 704 consecutive patients (400 women, 304 men) without thyroid disease underwent HRUS and CS examination of the thyroid gland. Number, size, location, echotexture and colour Doppler pattern of detected nodules were assessed. Two radiologists also assessed image quality of the two techniques.
Seven hundred and eleven thyroid nodules (size range 0.18-4.1 cm; mean: 1.1 cm) were detected in 233 subjects (33.1%). Of these, 416 (58.5%) were found in 143 women whereas 295 (41.5%) were detected in 90 men. In both genders, the number of detected nodules increased with age, with the highest prevalence in the seventh decade (p<0.001). There were 461/711 (64.9%) thyroid nodules that were hypoechoic, and 449/711 (63.1%) had peripheral vascularity only (p<0.001). Fine-needle aspiration (FNA) revealed no malignancies. CS was graded better than HRUS in 621/711 (87.3%) cases (p<0.001).
The prevalence of benign, small, hypoechoic thyroid nodules with peripheral vascularity was high in our series, thus suggesting a conservative approach. CS provided better image quality compared with HRUS.
我们的目的是评估通过高分辨率超声（HRUS）筛查的成年人群中甲状腺结节的发生率和超声特征，并评估实时空间复合超声（CS）在图像质量方面的作用。
共有704例无甲状腺疾病的连续患者（400名女性，304名男性）接受了甲状腺的HRUS和CS检查。评估检测到的结节的数量、大小、位置、回声纹理和彩色多普勒模式。两名放射科医生还评估了这两种技术的图像质量。
在233名受试者（33.1%）中检测到711个甲状腺结节（大小范围0.18 - 4.1 cm；平均：1.1 cm）。其中，143名女性中发现416个（58.5%），90名男性中检测到295个（41.5%）。在两性中，检测到的结节数量均随年龄增加，在七十岁时患病率最高（p<0.001）。711个甲状腺结节中有461个（64.9%）为低回声，449个（63.1%）仅具有周边血管（p<0.001）。细针穿刺（FNA）未发现恶性肿瘤。在711例病例中的621例（87.3%）中，CS的分级优于HRUS（p<0.001）。
在我们的系列研究中，具有周边血管的良性、小的、低回声甲状腺结节的患病率较高，因此提示采取保守方法。与HRUS相比，CS提供了更好的图像质量。
