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内脏动脉狭窄的临床意义。

Clinical significance of splanchnic artery stenosis.

作者信息

Mensink P B F, van Petersen A S, Geelkerken R H, Otte J A, Huisman A B, Kolkman J J

机构信息

Department of Internal Medicine and Gastroenterology, Medisch Spectrum Twente, Enschede, The Netherlands.

出版信息

Br J Surg. 2006 Nov;93(11):1377-82. doi: 10.1002/bjs.5481.

Abstract

BACKGROUND

The clinical relevance of splanchnic artery stenosis is often unclear. Gastric exercise tonometry enables the identification of patients with actual gastrointestinal ischaemia. A large group of patients with splanchnic artery stenosis was studied using standard investigations, including tonometry.

METHODS

Patients referred with possible intestinal ischaemia were analysed prospectively, using duplex imaging, conventional abdominal angiography and tonometry. All results were discussed within a multidisciplinary team.

RESULTS

Splanchnic stenoses were found in 157 (49.7 percent) of 316 patients; 95 patients (60.5 percent) had one-vessel, 54 (34.4 percent) two-vessel and eight (5.1 percent) had three-vessel disease. Chronic splanchnic syndrome was diagnosed in 107 patients (68.2 percent), 54 (57 percent) with single-vessel, 45 (83 percent) with two-vessel and all eight with three-vessel stenoses. Treatment was undertaken in 95 patients, 62 by surgery and 33 by endovascular techniques. After a median follow-up of 43 months, 84 percent of patients were symptom free.

CONCLUSION

Gastric exercise tonometry proved crucial in the evaluation of possible intestinal ischaemia. Comparing patients with single- and multiple-vessel stenoses, there were significant differences in clinical presentation and mortality rates.

摘要

背景

内脏动脉狭窄的临床相关性往往不明确。胃运动张力测定法能够识别实际存在胃肠道缺血的患者。我们使用包括张力测定法在内的标准检查方法,对一大组内脏动脉狭窄患者进行了研究。

方法

对因可能的肠道缺血而转诊的患者进行前瞻性分析,采用双功超声成像、传统腹部血管造影和张力测定法。所有结果均在多学科团队中进行讨论。

结果

316例患者中有157例(49.7%)发现内脏狭窄;95例患者(60.5%)为单支血管病变,54例(34.4%)为双支血管病变,8例(5.1%)为三支血管病变。107例患者(68.2%)被诊断为慢性内脏综合征,单支血管病变患者中有54例(57%),双支血管病变患者中有45例(83%),三支血管狭窄患者8例全部确诊。95例患者接受了治疗,62例接受手术治疗,33例接受血管内技术治疗。中位随访时间为43个月后,84%的患者无症状。

结论

胃运动张力测定法在评估可能的肠道缺血方面被证明至关重要。比较单支血管和多支血管狭窄的患者,其临床表现和死亡率存在显著差异。

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