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慢性肠系膜缺血血管内治疗方法的叙述性综述

A Narrative Review of Endovascular Approaches for Chronic Mesenteric Ischemia.

作者信息

Nagatomi Satoru, Kanamori Daigo, Yamamoto Hiroshi

机构信息

Department of Radiology, Sumitomo Hospital, Japan.

出版信息

Interv Radiol (Higashimatsuyama). 2025 Aug 1;10:e20240057. doi: 10.22575/interventionalradiology.2024-0057. eCollection 2025.

DOI:10.22575/interventionalradiology.2024-0057
PMID:40918240
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12408245/
Abstract

Chronic mesenteric ischemia typically presents with postprandial abdominal pain and weight loss due to atherosclerotic stenosis of mesenteric arteries. Endovascular treatment has become the first-line management, demonstrating lower early mortality and fewer complications compared to open surgery. Recent evidence shows that covered stents provide superior long-term outcomes, with better primary patency and freedom from reintervention than bare-metal stents. While patient selection remains crucial, with endovascular treatment being preferred for older, higher-risk patients and shorter lesions, it offers shorter hospital stays and comparable survival rates to open surgery for most patients. This review provides a comprehensive overview of current endovascular management strategies for chronic mesenteric ischemia, including patient selection, technical considerations, and outcomes.

摘要

慢性肠系膜缺血通常表现为餐后腹痛和体重减轻,这是由于肠系膜动脉粥样硬化狭窄所致。血管内治疗已成为一线治疗方法,与开放手术相比,其早期死亡率更低,并发症更少。最近的证据表明,覆膜支架能提供更好的长期疗效,与裸金属支架相比,其初始通畅率更高,再次干预的可能性更小。虽然患者选择仍然至关重要,对于年龄较大、风险较高的患者以及较短病变,血管内治疗更为可取,但对于大多数患者而言,它能缩短住院时间,且生存率与开放手术相当。本综述全面概述了慢性肠系膜缺血目前的血管内治疗策略,包括患者选择、技术考量和治疗结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f4a3/12408245/22b495812fd0/2432-0935-10-e2024-0057-g005B.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f4a3/12408245/a1f73188a8ff/2432-0935-10-e2024-0057-g004A.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f4a3/12408245/cb27b9ef57b5/2432-0935-10-e2024-0057-g004B.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f4a3/12408245/3a85f147de7d/2432-0935-10-e2024-0057-g004C.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f4a3/12408245/370188ce89dd/2432-0935-10-e2024-0057-g005A.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f4a3/12408245/22b495812fd0/2432-0935-10-e2024-0057-g005B.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f4a3/12408245/eab564c17524/2432-0935-10-e2024-0057-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f4a3/12408245/74063df0e550/2432-0935-10-e2024-0057-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f4a3/12408245/6f1597a8c212/2432-0935-10-e2024-0057-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f4a3/12408245/a1f73188a8ff/2432-0935-10-e2024-0057-g004A.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f4a3/12408245/cb27b9ef57b5/2432-0935-10-e2024-0057-g004B.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f4a3/12408245/3a85f147de7d/2432-0935-10-e2024-0057-g004C.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f4a3/12408245/370188ce89dd/2432-0935-10-e2024-0057-g005A.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f4a3/12408245/22b495812fd0/2432-0935-10-e2024-0057-g005B.jpg

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本文引用的文献

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Covered Versus Bare-Metal Stents in Chronic Mesenteric Ischemia Treatment: A Systematic Review and Meta-Analysis.覆膜支架与裸金属支架在慢性肠系膜缺血治疗中的应用:一项系统评价和荟萃分析
Ann Vasc Surg. 2025 Apr;113:214-220. doi: 10.1016/j.avsg.2024.12.071. Epub 2025 Jan 24.
2
Covered versus bare-metal stenting of the mesenteric arteries in patients with chronic mesenteric ischaemia (CoBaGI): a multicentre, patient-blinded and investigator-blinded, randomised controlled trial.慢性肠系膜缺血患者肠系膜动脉覆膜支架与裸金属支架置入术(CoBaGI):一项多中心、患者和研究者双盲的随机对照试验
Lancet Gastroenterol Hepatol. 2024 Apr;9(4):299-309. doi: 10.1016/S2468-1253(23)00402-8. Epub 2024 Jan 29.
3
Advancements in Treatment Strategies for Chronic Mesenteric Ischemia: A Comprehensive Review.
慢性肠系膜缺血治疗策略的进展:综述
J Clin Med. 2023 Nov 15;12(22):7112. doi: 10.3390/jcm12227112.
4
Endovascular revascularization of heavily calcified occlusion in superior mesenteric artery using Transcollateral approach.采用经侧支途径对肠系膜上动脉重度钙化闭塞病变进行血管内血运重建。
CVIR Endovasc. 2021 Jun 1;4(1):45. doi: 10.1186/s42155-021-00232-8.
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Midterm results after covered stenting of the superior mesenteric artery.经覆膜支架治疗的肠系膜上动脉中期结果。
J Vasc Surg. 2021 Sep;74(3):902-909.e3. doi: 10.1016/j.jvs.2021.02.038. Epub 2021 Mar 6.
6
Chronic mesenteric ischemia: Clinical practice guidelines from the Society for Vascular Surgery.慢性肠系膜缺血:血管外科学会临床实践指南。
J Vasc Surg. 2021 Jan;73(1S):87S-115S. doi: 10.1016/j.jvs.2020.10.029. Epub 2020 Nov 7.
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European guidelines on chronic mesenteric ischaemia - joint United European Gastroenterology, European Association for Gastroenterology, Endoscopy and Nutrition, European Society of Gastrointestinal and Abdominal Radiology, Netherlands Association of Hepatogastroenterologists, Hellenic Society of Gastroenterology, Cardiovascular and Interventional Radiological Society of Europe, and Dutch Mesenteric Ischemia Study group clinical guidelines on the diagnosis and treatment of patients with chronic mesenteric ischaemia.欧洲慢性肠系膜缺血指南 - 联合欧洲胃肠病学、欧洲胃肠病学、内镜和营养学会、欧洲胃肠道和腹部放射学会、荷兰肝胆病学会、希腊胃肠病学会、心血管和介入放射学会和荷兰肠系膜缺血研究小组的临床指南,用于诊断和治疗慢性肠系膜缺血患者。
United European Gastroenterol J. 2020 May;8(4):371-395. doi: 10.1177/2050640620916681. Epub 2020 Apr 16.
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Improving midterm results justify the continued use of bare-metal stents for endovascular therapy for chronic mesenteric ischemia.改善中期结果证明了在慢性肠系膜缺血的血管内治疗中继续使用裸金属支架是合理的。
J Vasc Surg. 2020 Jan;71(1):111-120. doi: 10.1016/j.jvs.2019.01.094. Epub 2019 Jul 18.
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