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调强放射治疗与口干症

Intensity-modulated radiation therapy and xerostomia.

作者信息

Chambers Mark S, Weber Randal S, Garden Adam S

机构信息

Department of Head and Neck Surgery, University of Texas M.D. Anderson Cancer Center, Houston, Texas 77030, USA.

出版信息

J Calif Dent Assoc. 2006 Sep;34(9):743-8.

PMID:17022299
Abstract

Conformal radiation with intensity-modulated radiation therapy, IMRT, is a radiation technique that potentially can minimize the dose to salivary glands and thereby decrease the incidence of xerostomia. Precise target determination and delineation is most important when using salivary gland-sparing techniques of IMRT. The reduction of xerostomia may be achieved by sparing the salivary glands on the noninvolved oral cavity and keeping the mean parotid gland dose of < 26-30 Gy if the treatment of disease is not compromised and parotid function preservation is desired.

摘要

适形放疗联合调强放疗(IMRT)是一种放射技术,有可能将唾液腺的剂量降至最低,从而降低口干症的发生率。在使用IMRT的唾液腺保留技术时,精确的靶区确定和勾画最为重要。如果疾病治疗不受影响且希望保留腮腺功能,通过保留未受累口腔的唾液腺并使腮腺平均剂量<26 - 30 Gy,可能实现口干症的减轻。

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