Kostron H, Plangger C, Russegger L
Universitätsklinik für Neurochirurgie, Innsbruck.
Wien Klin Wochenschr. 1990 Sep 28;102(18):536-8.
Persistent trigeminal neuralgia, herpes zoster neuralgia of the first division of the trigeminal nerve and pain caused by cancer situated in the head and neck pose frustrating problems for patients and physicians. Tractotomy and/or partial vertical nucleotomy of the subnucleus caudalis nervi trigemini offers a logical approach to the treatment of such pain, since these structures contain fibres of the Vth nerve, as well as the somatosensory fibres of the VIIth, IXth and Xth nerve. Tactile and some thermal sensitivity of the face is preserved and anaesthesia dolorosa and keratitis neuroparalytica is avoided. Over the past 30 years 370 patients with therapy-refractory trigeminal pain, pain due to cancer of the head and neck and herpes zoster trigeminal pain were treated by means of tractotomy (personal series of V. Grunert), including 30 patients who underwent partial vertical nucleotomy. The mean age of the patients was 68 years (range 54-84 years). The mortality in this series was 0.9% (4 patients; one operative mortality due to air embolism, one postoperative cardiac failure following myocardial infarction and two intracerebral haematomas). 60% of the patients with persistent trigeminal neuralgia were pain-free and 28% improved, whereas 12% were unchanged or suffered from recurrent pain. Of the patients with cancer who complained of pain derived from the Vth, VIIth, IXth and Xth nerve, 40% demonstrated marked pain relief and 60% showed no improvement. Tractotomy and partial vertical nucleotomy offer a valuable method in experienced hands for relieving pain where other methods have failed.
持续性三叉神经痛、三叉神经第一支的带状疱疹神经痛以及头颈部癌症引起的疼痛给患者和医生带来了令人沮丧的问题。三叉神经尾侧亚核的束切断术和/或部分垂直核切断术为治疗此类疼痛提供了一种合理的方法,因为这些结构包含第五神经的纤维以及第七、第九和第十神经的躯体感觉纤维。面部的触觉和部分热敏感性得以保留,避免了痛性麻木和麻痹性角膜炎。在过去30年中,370例治疗难治性三叉神经痛、头颈部癌症引起的疼痛和带状疱疹三叉神经痛患者接受了束切断术治疗(V. Grunert的个人系列病例),其中30例患者接受了部分垂直核切断术。患者的平均年龄为68岁(范围54 - 84岁)。该系列病例中的死亡率为0.9%(4例患者;1例因空气栓塞导致手术死亡,1例术后心肌梗死后心力衰竭,2例脑内血肿)。60%的持续性三叉神经痛患者疼痛消失,28%有所改善,而12%无变化或疼痛复发。在抱怨有来自第五、第七、第九和第十神经疼痛的癌症患者中,40%疼痛明显缓解,60%无改善。在经验丰富的医生手中,束切断术和部分垂直核切断术为其他方法治疗失败的疼痛缓解提供了一种有价值的方法。