Lee Pi-Chang, Tai Ching-Tai, Lin Yenn-Jiang, Liu Tu-Ying, Huang Bien-Hsien, Higa Satoshi, Yuniadi Yoga, Lee Kun-Tai, Hwang Betau, Chen Shih-Ann
Department of Pediatrics, Taipei Veterans General Hospital and National Yang-Ming University, Taipei, Taiwan.
Int J Cardiol. 2007 May 31;118(2):154-63. doi: 10.1016/j.ijcard.2006.08.003. Epub 2006 Oct 4.
Atrioventricular nodal reentrant tachycardia (AVNRT) is the most common supraventricular tachycardia in adulthood. Although selective ablation of the slow AV nodal pathway can cure AVNRT, accidental AV block may occur. The details on the electrophysiologic characteristics, quantitative data on the voltage inside Koch's triangle, and the use of three-dimensional noncontact mapping to facilitate the catheter ablation of AVNRT associated with a high-risk for AV block or other arrhythmias have been limited.
Nine patients (M/F=5/4, 34+/-23 years, range 17-76) with clinically documented AVNRT were included. All patients had undergone previous sessions for slow AV nodal pathway ablation but they had failed, because of repetitive episodes of complete AV block during the RF energy applications. Further, one patient had a complex anatomy and 4 patients were associated with other tachycardias, respectively. The electrophysiologic studies revealed that 4 patients had the slow-fast, 4 the slow-intermediate and one the fast-intermediate form of AVNRT. Noncontact mapping demonstrated two types of antegrade AV nodal conduction, markedly differing sites of the earliest atrial activation during retrograde VA conduction, and a lower range of voltage within Koch's triangle. The lowest border of the retrograde conduction region was defined on the map, and the application of the RF energy was delivered below that border to prevent the occurrence of AV block. The distance between the successful ablation lesions and the lowest border of the retrograde conduction region was significantly shorter in the patients with the slow-intermediate form of AVNRT than in those with the slow-fast form (5.5+/-3.4 vs. 15+/-7.6 mm; p<0.05). After the ablation procedure, either rapid pacing or extrastimulation could not induce any tachycardia, and there was no recurrence during the follow-up (10.3+/-5.4, 2 to 22 months).
Noncontact mapping could effectively demonstrate the antegrade and retrograde atrionodal conduction patterns, electrophysiologic characteristics of Koch's triangle, and guide the successful catheter ablation in difficult AVNRT cases.
房室结折返性心动过速(AVNRT)是成人最常见的室上性心动过速。尽管选择性消融房室结慢径可治愈AVNRT,但可能会意外发生房室传导阻滞。关于电生理特征、科赫三角内电压的定量数据以及使用三维非接触式标测以促进与房室传导阻滞或其他心律失常高风险相关的AVNRT导管消融的详细信息一直有限。
纳入9例经临床记录确诊为AVNRT的患者(男/女=5/4,34±23岁,范围17 - 76岁)。所有患者既往均接受过房室结慢径消融术,但均失败,原因是在射频能量施加过程中反复出现完全性房室传导阻滞。此外,1例患者解剖结构复杂,4例患者分别合并其他心动过速。电生理研究显示,4例患者为慢 - 快型AVNRT,4例为慢 - 中间型,1例为快 - 中间型。非接触式标测显示了两种类型的房室前向传导、逆行VA传导期间最早心房激动部位明显不同,以及科赫三角内较低的电压范围。在标测图上确定了逆行传导区域的最低边界,并在该边界下方施加射频能量以防止房室传导阻滞的发生。慢 - 中间型AVNRT患者成功消融灶与逆行传导区域最低边界之间的距离明显短于慢 - 快型患者(5.5±3.4 vs. 15±7.6 mm;p<0.05)。消融术后,快速起搏或额外刺激均不能诱发任何心动过速,随访期间(10.3±5.4,2至22个月)无复发。
非接触式标测可有效显示房室结的前向和逆向传导模式、科赫三角的电生理特征,并指导困难AVNRT病例的成功导管消融。