Willems S, Chen X, Hindricks G, Kottkamp H, Rotman B, Haverkamp W, Breithardt G, Borggrefe M
Medizinische Klinik und Poliklinik (Kardiologie/Angiologie), Westfälische Wilhelms-Universität Münster.
Z Kardiol. 1994 Feb;83(2):165-72.
AV-nodal reentrant tachycardia (AVNRT) is a common cause of recurrent supraventricular tachycardia. Currently, catheter ablation of either slow or fast pathway are nonpharmacologic options for the treatment of patients with AVNRT. Radiofrequency (RF) catheter ablation of the fast pathway was attempted in 35 patients (aged 46.7 +/- 15 years; 12 m, 23 f) with recurrent AVNRT. RF energy (25-50 watt, 30-90 s) was delivered to the anterior right atrial septum. The catheter was placed posterior to the largest His bundle deflection. AV conduction was monitored during continuous pacing of the high right atrium while the RF current was applied. RF-ablation was acutely successful using a mean of 6.5 +/- 6.2 impulses in 31 patients. Late spontaneous block of the slow pathway occurred in one patient (pat. 17) with an unsuccessful initial attempt of fast pathway ablation. PQ and AH interval increased significantly after the ablation procedure (PQ: from 149 +/- 27 to 208 +/- 34 ms, AH: from 76 +/- 22 to 131 +/- 38 ms; p value: < 0.0001). Acute interruption of retrograde VA conduction was the result in 23 patients. Six patients (17%) had a recurrence of AVNRT during a follow-up period of 11.9 +/- 7.5 months. Five of 6 patients underwent a second successful procedure. Complete AV block occurred in 3 of the first 10 consecutive patients and in none of the subsequent 25 patients (overall incidence: 8.6%). Thus, RF ablation of the fast retrograde pathway is an effective method for the curative treatment of AVNRT.(ABSTRACT TRUNCATED AT 250 WORDS)
房室结折返性心动过速(AVNRT)是复发性室上性心动过速的常见病因。目前,慢径或快径导管消融是治疗AVNRT患者的非药物选择。对35例(年龄46.7±15岁;男性12例,女性23例)复发性AVNRT患者尝试进行快径射频(RF)导管消融。将RF能量(25 - 50瓦,30 - 90秒)施加于右前房间隔。导管置于最大希氏束电位后方。在施加RF电流时,于高位右心房持续起搏期间监测房室传导。31例患者平均使用6.5±6.2次脉冲,RF消融即刻成功。1例患者(患者17)快径消融初始尝试未成功,随后出现慢径迟发性自发阻滞。消融术后PQ和AH间期显著增加(PQ:从149±27毫秒增至208±34毫秒,AH:从76±22毫秒增至131±38毫秒;p值:<0.0001)。23例患者出现逆行VA传导急性中断。6例患者(17%)在11.9±7.5个月的随访期内AVNRT复发。6例患者中有5例再次成功接受手术。连续的前10例患者中有3例发生完全性房室传导阻滞,随后的25例患者中无1例发生(总发生率:8.6%)。因此,快径逆行射频消融是根治AVNRT的有效方法。(摘要截取自250字)