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含粘性纤维营养棒对2型糖尿病患者饱腹感的影响。

Effect of a viscous fiber-containing nutrition bar on satiety of patients with type 2 diabetes.

作者信息

Chow Jomay, Choe Yong S, Noss Michael J, Robinson Kay J, Dugle Janis E, Acosta Sonja H, Garleb Keith A

机构信息

Ross Products Division, Abbott Laboratories, Columbus, OH 43215-1724, USA.

出版信息

Diabetes Res Clin Pract. 2007 Jun;76(3):335-40. doi: 10.1016/j.diabres.2006.09.013. Epub 2006 Oct 4.

Abstract

To assess the satiety-promoting effect of a novel viscous fiber-containing nutrition bar, overweight and obese adult subjects with type 2 diabetes (n=99) were randomized into a double blind, crossover study. They were fed a 300kcal lunch consisting of viscous fiber-containing nutrition bars (VF) or commercial nutrition control bars designed for people with diabetes (CH). VF resulted in a 27.1% increase in fullness (p<0.05), a 15.8% decrease in prospective consumption (p<0.001), and a 14.2% decrease in hunger (p<0.001) in the 120-240min post-lunch areas under the curve (AUC) compared to CH, but no differences were observed for nausea or thirst (p>0.05). Similar results were noted for 0-300min AUC values. VF were associated with greater frequencies and intensities of abdominal distention (p<0.001) and flatulence (p<0.001), and greater frequency of stools (p<0.001) compared to CH, but there were no differences in mean or maximum (loosest) stool consistency (p>0.05). Overall, these results suggest that VF could be a useful tool in weight management of type 2 diabetes.

摘要

为评估一种新型含粘性纤维营养棒的促饱腹感效果,将99名超重和肥胖的2型糖尿病成年受试者随机分为双盲交叉研究。他们分别食用了一份300千卡的午餐,其中一份午餐由含粘性纤维的营养棒(VF)组成,另一份午餐由专为糖尿病患者设计的商业营养对照棒(CH)组成。与CH相比,VF在午餐后120 - 240分钟曲线下面积(AUC)内,饱腹感增加了27.1%(p<0.05),预期摄入量减少了15.8%(p<0.001),饥饿感减少了14.2%(p<0.001),但在恶心或口渴方面未观察到差异(p>0.05)。0 - 300分钟AUC值也有类似结果。与CH相比,VF与腹胀(p<0.001)、肠胃胀气(p<0.001)的频率和强度更高以及排便频率更高(p<0.001)相关,但在粪便平均或最大(最稀)稠度方面没有差异(p>0.05)。总体而言,这些结果表明VF可能是2型糖尿病体重管理中的一种有用工具。

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