Fujisawa Takashi, Uchikoga Osamu, Seki Yasumichi, Kitaura Keisuke, Mori Toshiyuki, Sano Wataru, Ouchi Sachiko, Hirano Hirotsugu
Department of Internal Medicine, Nippon Steel Hirohata Hospital.
Nihon Shokakibyo Gakkai Zasshi. 2006 Oct;103(10):1127-33.
A 78-year-old woman was admitted to our hospital for treatment of liver cirrhosis and an esophageal varix. Endoscopy revealed a protruding nodular lesion with a transparent smooth surface proximal to the pylorus, which was accompanied by a partly yellow-whitish spot. A depressed lesion with an even edge was found. Histologically, the protruding lesion and depressed lesion showed amyloid deposits, mainly in the mucosal layer. The lesions were found to correspond to AL type amyloidosis by immunochemical analysis. General examination showed no other amyloid deposits. Thus, we diagnosed localized amyloidosis of the stomach.
一名78岁女性因肝硬化和食管静脉曲张入院治疗。内镜检查发现幽门近端有一个突出的结节性病变，表面透明光滑，伴有部分黄白色斑点。还发现了一个边缘整齐的凹陷性病变。组织学检查显示，突出性病变和凹陷性病变均有淀粉样蛋白沉积，主要在黏膜层。免疫化学分析发现这些病变符合AL型淀粉样变性。全身检查未发现其他淀粉样蛋白沉积。因此，我们诊断为胃局限性淀粉样变性。
