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丘脑网状核的结构组织、神经化学特征及连接

Structural organization, neurochemical characteristics, and connections of the reticular nucleus of the thalamus.

作者信息

Nagaeva D V, Akhmadeev A V

机构信息

Department of Human and Animal Morphology and Physiology, Bashkir State University, Ufa.

出版信息

Neurosci Behav Physiol. 2006 Nov;36(9):987-95. doi: 10.1007/s11055-006-0134-5.

DOI:10.1007/s11055-006-0134-5
PMID:17024337
Abstract

This review analyzes current concepts of the structural organization and ultrastructure of the reticular nucleus of the thalamus (RNT) and the neurochemical characteristics of its neurons. The topography, cytoarchitectonics, and neuronal organization of this nucleus are considered in detail, as are questions of its neurogenesis. Neurochemical data clarifying the representation of neurotransmitter systems in the RNT and data on neuropeptides synthesized in its neurons are systematized. The complex ultrastructural organization of the RNT is characterized in terms of recent data from state-of-the-art immunocytochemical methods allowing localization of glutamatergic and GABAergic receptors on synaptic elements. Data on the afferent and efferent connections of the RNT demonstrate its influences on various parts of the brain and the specific features of its interactions with cortical formations.

摘要

本综述分析了丘脑网状核(RNT)的结构组织和超微结构的当前概念及其神经元的神经化学特征。详细探讨了该核的拓扑结构、细胞构筑和神经元组织,以及其神经发生问题。对阐明RNT中神经递质系统表现的神经化学数据和其神经元中合成的神经肽数据进行了系统化整理。根据最新的免疫细胞化学方法获得的最新数据,对RNT复杂的超微结构组织进行了表征,这些方法能够在突触元件上定位谷氨酸能和γ-氨基丁酸能受体。关于RNT传入和传出连接的数据表明了它对大脑各个部分的影响以及它与皮质结构相互作用的具体特征。

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