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[碘海醇(欧乃派克)所致药疹的临床分析]

[Clinical analysis of drug eruption due to iohexol (Omnipaque)].

作者信息

Akiyama M, Iijima M, Fujisawa R

机构信息

Department of Dermatology, Showa University School of Medicine.

出版信息

Nihon Hifuka Gakkai Zasshi. 1990 Sep;100(10):1057-60.

PMID:1702479
Abstract

We reported 7 cases of drug eruption due to Iohexol (Omnipaque) which was nonionic X-ray contrast agent without severe adverse reaction. They showed generalized edematous and erythematous plaques. The eruption appeared from 5 to 6 days after the examination when a patient had not been sensitized, or several hours after that when he/she had been already sensitized. No case showed any cross-sensitization with ionic contrast media, but some cases suggested the possibility of cross-sensitization among the nonionic contrast agents.

摘要

我们报告了7例因碘海醇(欧乃派克)引起的药疹,碘海醇是一种非离子型X线造影剂,未出现严重不良反应。患者表现为全身性水肿性红斑斑块。在未致敏患者中,药疹出现在检查后5至6天;而在已致敏患者中,药疹出现在检查后数小时。无一例患者对离子型造影剂有交叉致敏反应,但部分病例提示非离子型造影剂之间可能存在交叉致敏。

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