Chizhov N P, Smol'skaia T T, Baĭchenko P I, Luk'ianova R I, Teslenko V M, Bavra G P, Romanchenko I A, Shatalov E B, Ershov F I, Tazulakhova E B
Vopr Virusol. 1990 Sep-Oct;35(5):411-4.
Tolerance and interferon-inducing activity of amixine, an interferon inducer, was studied by the double-blind method clinically in healthy volunteers given tableted amixine orally in doses of 0.125-0.25 g by different schedules. According to clinical laboratory examinations and studies of indirect parameters of labor capacity amixine was found to be tolerable for man. The amount of interferon in the blood serum depended on the schedule of administration of the inducer, the optimal being 1-2 amixine tablets at least 2 days apart.
采用双盲法，对健康志愿者口服不同剂量（0.125 - 0.25克）片剂的混合干扰素诱导剂（一种干扰素诱导剂）的耐受性和诱导干扰素活性进行了临床研究，给药方案不同。根据临床实验室检查和劳动能力间接参数研究发现，混合干扰素诱导剂对人体是可耐受的。血清中干扰素的含量取决于诱导剂的给药方案，最佳方案是至少间隔2天服用1 - 2片混合干扰素诱导剂。
