Adukauskiene Dalia, Vitkauskiene Astra
Clinic of Intensive Care, Kaunas University of Medicine, Eiveniu 2, 50009 Kaunas, Lithuania.
Medicina (Kaunas). 2006;42(9):703-8.
Nosocomial pneumonia, especially ventilator-acquired pneumonia, has the greatest impact on patients' management in intensive care unit. Inappropriate initial antimicrobial treatment increases attributable and crude mortality from ventilator-acquired pneumonia. De-escalation therapy improves short-term survival of patients with ventilator-acquired pneumonia without increasing the emergence of resistant organisms.
医院获得性肺炎，尤其是呼吸机相关性肺炎，对重症监护病房患者的治疗影响最大。不恰当的初始抗菌治疗会增加呼吸机相关性肺炎的归因死亡率和粗死亡率。降阶梯治疗可提高呼吸机相关性肺炎患者的短期生存率，且不会增加耐药菌的出现。
